Cargando…

Epigenetic regulation of defense genes by histone deacetylase1 in human cell line-derived macrophages promotes intracellular survival of Leishmania donovani

Leishmania donovani, an intracellular protozoan parasite upon infection, encounters a range of antimicrobial factors within the host cells. Consequently, the parasite has evolved mechanisms to evade this hostile defense system through inhibition of macrophage activation that, in turn, enables parasi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roy, Gargi, Brar, Harsimran Kaur, Muthuswami, Rohini, Madhubala, Rentala
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176143/ https://www.ncbi.nlm.nih.gov/pubmed/32275661 http://dx.doi.org/10.1371/journal.pntd.0008167

Ejemplares similares

Chromatin-Remodeling Factor BRG1 Is a Negative Modulator of L. donovani in IFNγ Stimulated and Infected THP-1 Cells
por: Brar, Harsimran Kaur, et al.
Publicado: (2022)

The mitochondrial SIR2 related protein 2 (SIR2RP2) impacts Leishmania donovani growth and infectivity
por: Mittal, Nimisha, et al.
Publicado: (2017)

A Plant like Cytochrome P450 Subfamily CYP710C1 Gene in Leishmania donovani Encodes Sterol C-22 Desaturase and its Over-expression Leads to Resistance to Amphotericin B
por: Bansal, Ruby, et al.
Publicado: (2019)

Rapid diagnosis of Leishmania infection with a portable loop-mediated isothermal amplification device
por: Puri, Madhu, et al.
Publicado: (2021)

Glyoxalase I Gene Deletion Mutants of Leishmania donovani Exhibit Reduced Methylglyoxal Detoxification
por: Chauhan, Swati C., et al.
Publicado: (2009)

Genetically Engineered Ascorbic acid-deficient Live Mutants of Leishmania donovani induce long lasting Protective Immunity against Visceral Leishmaniasis
por: Anand, Sneha, et al.
Publicado: (2015)

Genetic Validation of Leishmania donovani Lysyl-tRNA Synthetase Shows that It Is Indispensable for Parasite Growth and Infectivity
por: Chadha, Sanya, et al.
Publicado: (2017)

Paromomycin Affects Translation and Vesicle-Mediated Trafficking as Revealed by Proteomics of Paromomycin –Susceptible –Resistant Leishmania donovani
por: Chawla, Bhavna, et al.
Publicado: (2011)

Characterization of Leishmania donovani Aquaporins Shows Presence of Subcellular Aquaporins Similar to Tonoplast Intrinsic Proteins of Plants
por: Biyani, Neha, et al.
Publicado: (2011)

Genetic manipulation of Leishmania donovani threonyl tRNA synthetase facilitates its exploration as a potential therapeutic target
por: Chadha, Sanya, et al.
Publicado: (2018)

A Unique Modification of the Eukaryotic Initiation Factor 5A Shows the Presence of the Complete Hypusine Pathway in Leishmania donovani
por: Chawla, Bhavna, et al.
Publicado: (2012)

Rapid diagnosis of Plasmodium falciparum malaria using a point-of-care loop-mediated isothermal amplification device
por: Puri, Madhu, et al.
Publicado: (2022)

Leishmania donovani Infection Causes Distinct Epigenetic DNA Methylation Changes in Host Macrophages
por: Marr, Alexandra K., et al.
Publicado: (2014)

Leishmania Donovani. Hamster macrophage interactions in vitro: cell entry, intracellular survival, and multiplication of amastigotes
por: Chang, K-P, et al.
Publicado: (1978)

Arginase Is Essential for Survival of Leishmania donovani Promastigotes but Not Intracellular Amastigotes
por: Boitz, Jan M., et al.
Publicado: (2016)

Unusual domain architecture of aminoacyl tRNA synthetases and their paralogs from Leishmania major
por: Gowri, V S, et al.
Publicado: (2012)

Recombinant human granulocyte/macrophage colony-stimulating factor activates intracellular killing of Leishmania donovani by human monocyte-derived macrophages
Publicado: (1987)

Macrophage Microbicidal Mechanisms In Vivo: Reactive Nitrogen versus Oxygen Intermediates in the Killing of Intracellular Visceral Leishmania donovani
por: Murray, Henry W., et al.
Publicado: (1999)

An Image-Based High-Content Screening Assay for Compounds Targeting Intracellular Leishmania donovani Amastigotes in Human Macrophages
por: Siqueira-Neto, Jair L., et al.
Publicado: (2012)

Leishmania donovani depletes labile iron pool to exploit iron uptake capacity of macrophage for its intracellular growth
por: Das, Nupur Kanti, et al.
Publicado: (2009)

The role of PD-1 in regulation of macrophage apoptosis and its subversion by Leishmania donovani
por: Roy, Shalini, et al.
Publicado: (2017)

Sphingosine-1-phosphate signaling in Leishmania donovani infection in macrophages
por: Arish, Mohd, et al.
Publicado: (2018)

Sensing Host Arginine Is Essential for Leishmania Parasites’ Intracellular Development
por: Goldman-Pinkovich, Adele, et al.
Publicado: (2020)

The arginine sensing and transport binding sites are distinct in the human pathogen Leishmania
por: Pawar, Harsh, et al.
Publicado: (2019)

Purification and Characterization of a Novel Intracellular Sucrase Enzyme of Leishmania donovani Promastigotes
por: Singh, Arpita, et al.
Publicado: (2016)

Intracellular Pathogen Leishmania donovani Activates Hypoxia Inducible Factor-1 by Dual Mechanism for Survival Advantage within Macrophage
por: Singh, Amit Kumar, et al.
Publicado: (2012)

LEISHMANIA DONOVANI IN THE PERIPHERAL BLOOD
por: Young, Charles W., et al.
Publicado: (1923)

Histone deacetylases in RA: epigenetics and epiphenomena
por: Grabiec, Aleksander M, et al.
Publicado: (2010)

Histone Deacetylases and Their Inhibitors in Cancer Epigenetics
por: Hassell, Kelly N.
Publicado: (2019)

Epigenetic Regulation of Host Defense Peptide Synthesis: Synergy Between Histone Deacetylase Inhibitors and DNA/Histone Methyltransferase Inhibitors
por: Whitmore, Melanie A., et al.
Publicado: (2022)

A small heat shock protein is essential for thermotolerance and intracellular survival of Leishmania donovani
por: Hombach, Antje, et al.
Publicado: (2014)

Role of Efflux Pumps and Intracellular Thiols in Natural Antimony Resistant Isolates of Leishmania donovani
por: Rai, Smita, et al.
Publicado: (2013)

Evaluation of synergy between host and pathogen-directed therapies against intracellular Leishmania donovani
por: Zahid, M. Shamim Hasan, et al.
Publicado: (2019)

Leishmania donovani Infection Enhances Lateral Mobility of Macrophage Membrane Protein Which Is Reversed by Liposomal Cholesterol
por: Ghosh, Moumita, et al.
Publicado: (2014)

Cholesterol Corrects Altered Conformation of MHC-II Protein in Leishmania donovani Infected Macrophages: Implication in Therapy
por: Roy, Koushik, et al.
Publicado: (2016)

Leishmania donovani-Induced Increase in Macrophage Bcl-2 Favors Parasite Survival
por: Pandey, Rajeev Kumar, et al.
Publicado: (2016)

Hemophagocytosis induced by Leishmania donovani infection is beneficial to parasite survival within macrophages
por: Morimoto, Ayako, et al.
Publicado: (2019)

Proteomic analysis of the secretome of Leishmania donovani
por: Silverman, J Maxwell, et al.
Publicado: (2008)

Surface antigens of Leishmania donovani promastigotes
Publicado: (1983)

Vaccine Development Against Leishmania donovani
por: Das, Amrita, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_h5hdtmm371t9pnpu9qukug0911