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Precise genomic mapping of 5-hydroxymethylcytosine via covalent tether-directed sequencing

5-hydroxymethylcytosine (5hmC) is the most prevalent intermediate on the oxidative DNA demethylation pathway and is implicated in regulation of embryogenesis, neurological processes, and cancerogenesis. Profiling of this relatively scarce genomic modification in clinical samples requires cost-effect...

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Detalles Bibliográficos
Autores principales:	Gibas, Povilas, Narmontė, Milda, Staševskij, Zdislav, Gordevičius, Juozas, Klimašauskas, Saulius, Kriukienė, Edita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Methods and Resources
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176277/ https://www.ncbi.nlm.nih.gov/pubmed/32275660 http://dx.doi.org/10.1371/journal.pbio.3000684

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