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Stochastic modeling reveals kinetic heterogeneity in post-replication DNA methylation

DNA methylation is a heritable epigenetic modification that plays an essential role in mammalian development. Genomic methylation patterns are dynamically maintained, with DNA methyltransferases mediating inheritance of methyl marks onto nascent DNA over cycles of replication. A recently developed e...

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Detalles Bibliográficos
Autores principales:	Busto-Moner, Luis, Morival, Julien, Ren, Honglei, Fahim, Arjang, Reitz, Zachary, Downing, Timothy L., Read, Elizabeth L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176288/ https://www.ncbi.nlm.nih.gov/pubmed/32275652 http://dx.doi.org/10.1371/journal.pcbi.1007195

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