Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling

It is well known that various developmental signals play diverse roles in hematopoietic stem and progenitor cell (HSPC) production; however, how these signaling pathways are orchestrated remains incompletely understood. Here, we report that Rab5c is essential for HSPC specification by endocytic traf...

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Detalles Bibliográficos
Autores principales: Heng, Jian, Lv, Peng, Zhang, Yifan, Cheng, Xinjie, Wang, Lu, Ma, Dongyuan, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176290/
https://www.ncbi.nlm.nih.gov/pubmed/32275659
http://dx.doi.org/10.1371/journal.pbio.3000696

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