Cargando…
Inhibitors of Hydrolases with an Acyl–Enzyme Intermediate
Peptidases and esterases are hydrolytic enzymes; 2–3% of all gene products are assigned to this group alone. They are therefore, an important group of target proteins for the design of new medicines and have a special importance for structure-based drug design. This is reflected in the fact that abo...
Autor principal: | Klebe, Gerhard |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176293/ http://dx.doi.org/10.1007/978-3-642-17907-5_23 |
Ejemplares similares
-
Acylation-coupled lipophilic induction of polarisation (Acyl-cLIP): a universal assay for lipid transferase and hydrolase enzymes
por: Lanyon-Hogg, Thomas, et al.
Publicado: (2019) -
Multiple-turnover thio-ATP hydrolase and phospho-enzyme intermediate formation activities catalyzed by an RNA enzyme
por: Saran, Dayal, et al.
Publicado: (2006) -
Novel Strategies for Upstream and Downstream Processing of Tannin Acyl Hydrolase
por: Rodríguez-Durán, Luis V., et al.
Publicado: (2011) -
Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide
por: Yamin, Rina, et al.
Publicado: (2009) -
Acyl Donor Intermediates in N‐Heterocyclic Carbene Catalysis: Acyl Azolium or Azolium Enolate?
por: Biswas, Animesh, et al.
Publicado: (2021)