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Polygenic Hyperlipidemias and Coronary Artery Disease Risk
Hyperlipidemia is a highly heritable risk factor for coronary artery disease (CAD). While monogenic familial hypercholesterolemia associates with severely increased CAD risk, it remains less clear to what extent a high polygenic load of a large number of LDL (low-density lipoprotein) cholesterol (LD...
Autores principales: | Ripatti, Pietari, Rämö, Joel T., Mars, Nina J., Fu, Yu, Lin, Jake, Söderlund, Sanni, Benner, Christian, Surakka, Ida, Kiiskinen, Tuomo, Havulinna, Aki S., Palta, Priit, Freimer, Nelson B., Widén, Elisabeth, Salomaa, Veikko, Tukiainen, Taru, Pirinen, Matti, Palotie, Aarno, Taskinen, Marja-Riitta, Ripatti, Samuli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176338/ https://www.ncbi.nlm.nih.gov/pubmed/32154731 http://dx.doi.org/10.1161/CIRCGEN.119.002725 |
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