Partial Inhibition of Glycolysis Reduces Atherogenesis Independent of Intraplaque Neovascularization in Mice

OBJECTIVE: Intraplaque neovascularization is an important feature of unstable human atherosclerotic plaques. However, its impact on plaque formation and stability is poorly studied. Because proliferating endothelial cells generate up to 85% of their ATP from glycolysis, we investigated whether pharm...

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Detalles Bibliográficos
Autores principales: Perrotta, Paola, Van der Veken, Bieke, Van Der Veken, Pieter, Pintelon, Isabel, Roosens, Laurence, Adriaenssens, Elias, Timmerman, Vincent, Guns, Pieter-Jan, De Meyer, Guido R.Y., Martinet, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176341/
https://www.ncbi.nlm.nih.gov/pubmed/32188275
http://dx.doi.org/10.1161/ATVBAHA.119.313692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176341/
https://www.ncbi.nlm.nih.gov/pubmed/32188275
http://dx.doi.org/10.1161/ATVBAHA.119.313692

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