STING couples with PI3K to regulate actin reorganization during BCR activation

The adaptor protein, STING (stimulator of interferon genes), has been rarely studied in adaptive immunity. We used Sting KO mice and a patient’s mutated STING cells to study the effect of STING deficiency on B cell development, differentiation, and BCR signaling. We found that STING deficiency promo...

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Detalles Bibliográficos
Autores principales: Jing, Yukai, Dai, Xin, Yang, Lu, Kang, Danqing, Jiang, Panpan, Li, Na, Cheng, Jiali, Li, Jingwen, Miller, Heather, Ren, Boxu, Gong, Quan, Yin, Wei, Liu, Zheng, Mattila, Pieta K., Ning, Qin, Sun, Jinqiao, Yu, Bing, Liu, Chaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176427/
https://www.ncbi.nlm.nih.gov/pubmed/32494627
http://dx.doi.org/10.1126/sciadv.aax9455

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