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CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1
Human casein kinase 1 delta (CK1δ) and epsilon (CK1ε) are members of a conserved family of abundant, ubiquitously expressed serine/threonine kinases that regulate multiple cellular processes including circadian rhythm and endocytosis. Here, we have investigated the localization and interactomes of e...
Autores principales: | Guillen, Rodrigo X., Beckley, Janel R., Chen, Jun-Song, Gould, Kathleen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176688/ https://www.ncbi.nlm.nih.gov/pubmed/32321936 http://dx.doi.org/10.1038/s41598-020-63669-2 |
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