Inhibition of Interleukin‐6/glycoprotein 130 signalling by Bazedoxifene ameliorates cardiac remodelling in pressure overload mice

The role of IL‐6 signalling in hypertensive heart disease and its sequelae is controversial. Our group demonstrated that Bazedoxifene suppressed IL‐6/gp130 signalling in cancer cells but its effect on myocardial pathology induced by pressure overload is still unknown. We explored whether Bazedoxifen...

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Detalles Bibliográficos
Autores principales: Shi, Wei, Ma, Haiyan, Liu, Tianshu, Yan, Dan, Luo, Pengcheng, Zhai, Maocai, Tao, Jingwen, Huo, Shengqi, Guo, Junyi, Li, Chenglong, Lin, Jiayuh, Zhang, Cuntai, Li, Sheng, Lv, Jiagao, Lin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176848/
https://www.ncbi.nlm.nih.gov/pubmed/32164044
http://dx.doi.org/10.1111/jcmm.15147

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