Glucocorticoid‐transactivated TSC22D3 attenuates hypoxia‐ and diabetes‐induced Müller glial galectin‐1 expression via HIF‐1α destabilization

Galectin‐1/LGALS1, a newly recognized angiogenic factor, contributes to the pathogenesis of diabetic retinopathy (DR). Recently, we demonstrated that glucocorticoids suppressed an interleukin‐1β‐driven inflammatory pathway for galectin‐1 expression in vitro and in vivo. Here, we show glucocorticoid‐...

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Detalles Bibliográficos
Autores principales: Kanda, Atsuhiro, Hirose, Ikuyo, Noda, Kousuke, Murata, Miyuki, Ishida, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176855/
https://www.ncbi.nlm.nih.gov/pubmed/32150332
http://dx.doi.org/10.1111/jcmm.15116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176855/
https://www.ncbi.nlm.nih.gov/pubmed/32150332
http://dx.doi.org/10.1111/jcmm.15116

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