Efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates

Herein, we present an efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates. Each step of the synthesis was optimized to provide excellent yields. Moreover, the absolute configuration of the obtained compounds was determined by X-ray analysis, which proved the stereochemist...

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Detalles Bibliográficos
Autores principales: Kaźmierczak, Marcin, Koroniak, Henryk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176923/
https://www.ncbi.nlm.nih.gov/pubmed/32362949
http://dx.doi.org/10.3762/bjoc.16.69
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author Kaźmierczak, Marcin
Koroniak, Henryk
author_facet Kaźmierczak, Marcin
Koroniak, Henryk
author_sort Kaźmierczak, Marcin
collection PubMed
description Herein, we present an efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates. Each step of the synthesis was optimized to provide excellent yields. Moreover, the absolute configuration of the obtained compounds was determined by X-ray analysis, which proved the stereochemistry that was proposed based on NMR studies.
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spelling pubmed-71769232020-05-01 Efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates Kaźmierczak, Marcin Koroniak, Henryk Beilstein J Org Chem Full Research Paper Herein, we present an efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates. Each step of the synthesis was optimized to provide excellent yields. Moreover, the absolute configuration of the obtained compounds was determined by X-ray analysis, which proved the stereochemistry that was proposed based on NMR studies. Beilstein-Institut 2020-04-16 /pmc/articles/PMC7176923/ /pubmed/32362949 http://dx.doi.org/10.3762/bjoc.16.69 Text en Copyright © 2020, Kaźmierczak and Koroniak https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Kaźmierczak, Marcin
Koroniak, Henryk
Efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates
title Efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates
title_full Efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates
title_fullStr Efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates
title_full_unstemmed Efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates
title_short Efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates
title_sort efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176923/
https://www.ncbi.nlm.nih.gov/pubmed/32362949
http://dx.doi.org/10.3762/bjoc.16.69
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