Recent advances in Cu-catalyzed C(sp(3))–Si and C(sp(3))–B bond formation

Numerous reactions generating C–Si and C–B bonds are in focus owing to the importance of incorporating silicon or boron into new or existing drugs, in addition to their use as building blocks in cross-coupling reactions en route to various targets of both natural and unnatural origins. In this revie...

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Detalles Bibliográficos
Autores principales: Takale, Balaram S, Thakore, Ruchita R, Etemadi-Davan, Elham, Lipshutz, Bruce H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176932/
https://www.ncbi.nlm.nih.gov/pubmed/32362947
http://dx.doi.org/10.3762/bjoc.16.67
Descripción
Sumario:Numerous reactions generating C–Si and C–B bonds are in focus owing to the importance of incorporating silicon or boron into new or existing drugs, in addition to their use as building blocks in cross-coupling reactions en route to various targets of both natural and unnatural origins. In this review, recent protocols relying on copper-catalyzed sp(3) carbon–silicon and carbon–boron bond-forming reactions are discussed.

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