Recent advances in Cu-catalyzed C(sp(3))–Si and C(sp(3))–B bond formation

Numerous reactions generating C–Si and C–B bonds are in focus owing to the importance of incorporating silicon or boron into new or existing drugs, in addition to their use as building blocks in cross-coupling reactions en route to various targets of both natural and unnatural origins. In this revie...

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Autores principales: Takale, Balaram S, Thakore, Ruchita R, Etemadi-Davan, Elham, Lipshutz, Bruce H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176932/
https://www.ncbi.nlm.nih.gov/pubmed/32362947
http://dx.doi.org/10.3762/bjoc.16.67
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author Takale, Balaram S
Thakore, Ruchita R
Etemadi-Davan, Elham
Lipshutz, Bruce H
author_facet Takale, Balaram S
Thakore, Ruchita R
Etemadi-Davan, Elham
Lipshutz, Bruce H
author_sort Takale, Balaram S
collection PubMed
description Numerous reactions generating C–Si and C–B bonds are in focus owing to the importance of incorporating silicon or boron into new or existing drugs, in addition to their use as building blocks in cross-coupling reactions en route to various targets of both natural and unnatural origins. In this review, recent protocols relying on copper-catalyzed sp(3) carbon–silicon and carbon–boron bond-forming reactions are discussed.
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spelling pubmed-71769322020-05-01 Recent advances in Cu-catalyzed C(sp(3))–Si and C(sp(3))–B bond formation Takale, Balaram S Thakore, Ruchita R Etemadi-Davan, Elham Lipshutz, Bruce H Beilstein J Org Chem Review Numerous reactions generating C–Si and C–B bonds are in focus owing to the importance of incorporating silicon or boron into new or existing drugs, in addition to their use as building blocks in cross-coupling reactions en route to various targets of both natural and unnatural origins. In this review, recent protocols relying on copper-catalyzed sp(3) carbon–silicon and carbon–boron bond-forming reactions are discussed. Beilstein-Institut 2020-04-15 /pmc/articles/PMC7176932/ /pubmed/32362947 http://dx.doi.org/10.3762/bjoc.16.67 Text en Copyright © 2020, Takale et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Review
Takale, Balaram S
Thakore, Ruchita R
Etemadi-Davan, Elham
Lipshutz, Bruce H
Recent advances in Cu-catalyzed C(sp(3))–Si and C(sp(3))–B bond formation
title Recent advances in Cu-catalyzed C(sp(3))–Si and C(sp(3))–B bond formation
title_full Recent advances in Cu-catalyzed C(sp(3))–Si and C(sp(3))–B bond formation
title_fullStr Recent advances in Cu-catalyzed C(sp(3))–Si and C(sp(3))–B bond formation
title_full_unstemmed Recent advances in Cu-catalyzed C(sp(3))–Si and C(sp(3))–B bond formation
title_short Recent advances in Cu-catalyzed C(sp(3))–Si and C(sp(3))–B bond formation
title_sort recent advances in cu-catalyzed c(sp(3))–si and c(sp(3))–b bond formation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176932/
https://www.ncbi.nlm.nih.gov/pubmed/32362947
http://dx.doi.org/10.3762/bjoc.16.67
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