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Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties

We report on the synthesis of composite nanobeads with antibacterial properties. The particles consist of polystyrene cores that are surrounded by sulfonic gel shells with embedded silver nanoparticles. The nanocomposite beads are prepared by sulfonation of polystyrene particles followed by accumula...

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Detalles Bibliográficos
Autores principales: Bartel, Marta, Markowska, Katarzyna, Strawski, Marcin, Wolska, Krystyna, Mazur, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176999/
https://www.ncbi.nlm.nih.gov/pubmed/32363129
http://dx.doi.org/10.3762/bjnano.11.49
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author Bartel, Marta
Markowska, Katarzyna
Strawski, Marcin
Wolska, Krystyna
Mazur, Maciej
author_facet Bartel, Marta
Markowska, Katarzyna
Strawski, Marcin
Wolska, Krystyna
Mazur, Maciej
author_sort Bartel, Marta
collection PubMed
description We report on the synthesis of composite nanobeads with antibacterial properties. The particles consist of polystyrene cores that are surrounded by sulfonic gel shells with embedded silver nanoparticles. The nanocomposite beads are prepared by sulfonation of polystyrene particles followed by accumulation of silver ions in the shell layer and subsequent reduction with sodium borohydride. The resulting material has been characterized by electron microscopy, vibrational and X-ray photoelectron spectroscopy and several other experimental techniques. It was shown that sodium borohydride reduces silver ions embedded in the gel layer producing silver nanoparticles but also transforms a fraction of sulfonic groups in the polymer to moieties with sulfur in a lower oxidation state, likely thiols. It is hypothesized that the generated thiol groups are anchoring the nanoparticles in the gel shell of the nanobeads stabilizing the whole structure. The silver-decorated nanobeads appear to be a promising material with considerable antimicrobial activity and were tested against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Staphylococcus epidermidis. The determined minimum inhibitory (MIC) and minimum biofilm inhibitory (MBIC) concentrations are comparable to those of non-incorporated silver nanoparticles.
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spelling pubmed-71769992020-05-01 Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties Bartel, Marta Markowska, Katarzyna Strawski, Marcin Wolska, Krystyna Mazur, Maciej Beilstein J Nanotechnol Full Research Paper We report on the synthesis of composite nanobeads with antibacterial properties. The particles consist of polystyrene cores that are surrounded by sulfonic gel shells with embedded silver nanoparticles. The nanocomposite beads are prepared by sulfonation of polystyrene particles followed by accumulation of silver ions in the shell layer and subsequent reduction with sodium borohydride. The resulting material has been characterized by electron microscopy, vibrational and X-ray photoelectron spectroscopy and several other experimental techniques. It was shown that sodium borohydride reduces silver ions embedded in the gel layer producing silver nanoparticles but also transforms a fraction of sulfonic groups in the polymer to moieties with sulfur in a lower oxidation state, likely thiols. It is hypothesized that the generated thiol groups are anchoring the nanoparticles in the gel shell of the nanobeads stabilizing the whole structure. The silver-decorated nanobeads appear to be a promising material with considerable antimicrobial activity and were tested against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Staphylococcus epidermidis. The determined minimum inhibitory (MIC) and minimum biofilm inhibitory (MBIC) concentrations are comparable to those of non-incorporated silver nanoparticles. Beilstein-Institut 2020-04-14 /pmc/articles/PMC7176999/ /pubmed/32363129 http://dx.doi.org/10.3762/bjnano.11.49 Text en Copyright © 2020, Bartel et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjnano/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Nanotechnology terms and conditions: (https://www.beilstein-journals.org/bjnano/terms)
spellingShingle Full Research Paper
Bartel, Marta
Markowska, Katarzyna
Strawski, Marcin
Wolska, Krystyna
Mazur, Maciej
Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties
title Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties
title_full Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties
title_fullStr Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties
title_full_unstemmed Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties
title_short Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties
title_sort silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176999/
https://www.ncbi.nlm.nih.gov/pubmed/32363129
http://dx.doi.org/10.3762/bjnano.11.49
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