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Endovascular Treatment of Intracerebral Giant Cell Arteritis
Background: Giant cell arteritis (GCA) is the most common primary systemic vasculitis predominantly affecting large and medium sized vessels. In rare cases, the vasculitis can affect the vessels of the brain. Results: We describe four cases of GCA with involvement of the cerebral vessels causing str...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177021/ https://www.ncbi.nlm.nih.gov/pubmed/32373053 http://dx.doi.org/10.3389/fneur.2020.00287 |
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author | Simonsen, Claus Z. Speiser, Lasse Hansen, Ib Tønder Jayne, David von Weitzel-Mudersbach, Paul |
author_facet | Simonsen, Claus Z. Speiser, Lasse Hansen, Ib Tønder Jayne, David von Weitzel-Mudersbach, Paul |
author_sort | Simonsen, Claus Z. |
collection | PubMed |
description | Background: Giant cell arteritis (GCA) is the most common primary systemic vasculitis predominantly affecting large and medium sized vessels. In rare cases, the vasculitis can affect the vessels of the brain. Results: We describe four cases of GCA with involvement of the cerebral vessels causing stroke. These cases were unresponsive to aggressive immunosuppression and we opted to treat with endovascular balloon dilatation of the stenotic areas. The procedure was safe. The four patients were treated in nine sessions and a total of 16 vessels were treated. We observed two dissections with no clinical influence on the patients. Discussion: In patients with stroke due to progressive GCA that is non-responsive to immunosuppression, endovascular therapy is feasible. |
format | Online Article Text |
id | pubmed-7177021 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71770212020-05-05 Endovascular Treatment of Intracerebral Giant Cell Arteritis Simonsen, Claus Z. Speiser, Lasse Hansen, Ib Tønder Jayne, David von Weitzel-Mudersbach, Paul Front Neurol Neurology Background: Giant cell arteritis (GCA) is the most common primary systemic vasculitis predominantly affecting large and medium sized vessels. In rare cases, the vasculitis can affect the vessels of the brain. Results: We describe four cases of GCA with involvement of the cerebral vessels causing stroke. These cases were unresponsive to aggressive immunosuppression and we opted to treat with endovascular balloon dilatation of the stenotic areas. The procedure was safe. The four patients were treated in nine sessions and a total of 16 vessels were treated. We observed two dissections with no clinical influence on the patients. Discussion: In patients with stroke due to progressive GCA that is non-responsive to immunosuppression, endovascular therapy is feasible. Frontiers Media S.A. 2020-04-16 /pmc/articles/PMC7177021/ /pubmed/32373053 http://dx.doi.org/10.3389/fneur.2020.00287 Text en Copyright © 2020 Simonsen, Speiser, Hansen, Jayne and von Weitzel-Mudersbach. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Simonsen, Claus Z. Speiser, Lasse Hansen, Ib Tønder Jayne, David von Weitzel-Mudersbach, Paul Endovascular Treatment of Intracerebral Giant Cell Arteritis |
title | Endovascular Treatment of Intracerebral Giant Cell Arteritis |
title_full | Endovascular Treatment of Intracerebral Giant Cell Arteritis |
title_fullStr | Endovascular Treatment of Intracerebral Giant Cell Arteritis |
title_full_unstemmed | Endovascular Treatment of Intracerebral Giant Cell Arteritis |
title_short | Endovascular Treatment of Intracerebral Giant Cell Arteritis |
title_sort | endovascular treatment of intracerebral giant cell arteritis |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177021/ https://www.ncbi.nlm.nih.gov/pubmed/32373053 http://dx.doi.org/10.3389/fneur.2020.00287 |
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