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Endovascular Treatment of Intracerebral Giant Cell Arteritis

Background: Giant cell arteritis (GCA) is the most common primary systemic vasculitis predominantly affecting large and medium sized vessels. In rare cases, the vasculitis can affect the vessels of the brain. Results: We describe four cases of GCA with involvement of the cerebral vessels causing str...

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Autores principales: Simonsen, Claus Z., Speiser, Lasse, Hansen, Ib Tønder, Jayne, David, von Weitzel-Mudersbach, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177021/
https://www.ncbi.nlm.nih.gov/pubmed/32373053
http://dx.doi.org/10.3389/fneur.2020.00287
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author Simonsen, Claus Z.
Speiser, Lasse
Hansen, Ib Tønder
Jayne, David
von Weitzel-Mudersbach, Paul
author_facet Simonsen, Claus Z.
Speiser, Lasse
Hansen, Ib Tønder
Jayne, David
von Weitzel-Mudersbach, Paul
author_sort Simonsen, Claus Z.
collection PubMed
description Background: Giant cell arteritis (GCA) is the most common primary systemic vasculitis predominantly affecting large and medium sized vessels. In rare cases, the vasculitis can affect the vessels of the brain. Results: We describe four cases of GCA with involvement of the cerebral vessels causing stroke. These cases were unresponsive to aggressive immunosuppression and we opted to treat with endovascular balloon dilatation of the stenotic areas. The procedure was safe. The four patients were treated in nine sessions and a total of 16 vessels were treated. We observed two dissections with no clinical influence on the patients. Discussion: In patients with stroke due to progressive GCA that is non-responsive to immunosuppression, endovascular therapy is feasible.
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spelling pubmed-71770212020-05-05 Endovascular Treatment of Intracerebral Giant Cell Arteritis Simonsen, Claus Z. Speiser, Lasse Hansen, Ib Tønder Jayne, David von Weitzel-Mudersbach, Paul Front Neurol Neurology Background: Giant cell arteritis (GCA) is the most common primary systemic vasculitis predominantly affecting large and medium sized vessels. In rare cases, the vasculitis can affect the vessels of the brain. Results: We describe four cases of GCA with involvement of the cerebral vessels causing stroke. These cases were unresponsive to aggressive immunosuppression and we opted to treat with endovascular balloon dilatation of the stenotic areas. The procedure was safe. The four patients were treated in nine sessions and a total of 16 vessels were treated. We observed two dissections with no clinical influence on the patients. Discussion: In patients with stroke due to progressive GCA that is non-responsive to immunosuppression, endovascular therapy is feasible. Frontiers Media S.A. 2020-04-16 /pmc/articles/PMC7177021/ /pubmed/32373053 http://dx.doi.org/10.3389/fneur.2020.00287 Text en Copyright © 2020 Simonsen, Speiser, Hansen, Jayne and von Weitzel-Mudersbach. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Simonsen, Claus Z.
Speiser, Lasse
Hansen, Ib Tønder
Jayne, David
von Weitzel-Mudersbach, Paul
Endovascular Treatment of Intracerebral Giant Cell Arteritis
title Endovascular Treatment of Intracerebral Giant Cell Arteritis
title_full Endovascular Treatment of Intracerebral Giant Cell Arteritis
title_fullStr Endovascular Treatment of Intracerebral Giant Cell Arteritis
title_full_unstemmed Endovascular Treatment of Intracerebral Giant Cell Arteritis
title_short Endovascular Treatment of Intracerebral Giant Cell Arteritis
title_sort endovascular treatment of intracerebral giant cell arteritis
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177021/
https://www.ncbi.nlm.nih.gov/pubmed/32373053
http://dx.doi.org/10.3389/fneur.2020.00287
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