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The tumor microenvironment and radiotherapy response; a central role for cancer-associated fibroblasts

Tumor growth is not only dictated by events involving tumor cells, but also by the environment they reside in, the so-called tumor microenvironment (TME). In the TME, cancer-associated fibroblasts (CAFs) are often the predominant cell type. CAFs were long considered to be of limited importance in th...

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Detalles Bibliográficos
Autores principales: Ansems, Marleen, Span, Paul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177030/
https://www.ncbi.nlm.nih.gov/pubmed/32337377
http://dx.doi.org/10.1016/j.ctro.2020.04.001