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Ligand-Mediated Targeting of Cytokine Interleukin-27 Enhances Its Bioactivity In Vivo
We have examined the role of a novel targeted cytokine, interleukin-27 (IL-27), modified at the C terminus with a dual targeting and therapeutic heptapeptide, in treating prostate cancer. IL-27 has shown promise in halting tumor growth and mediating tumor regression in several cancer models, includi...
Autores principales: | Figueiredo, Marxa L., Figueiredo Neto, Manoel, Salameh, Janelle Wes, Decker, Richard E., Letteri, Rachel, Chan-Seng, Delphine, Emrick, Todd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177159/ https://www.ncbi.nlm.nih.gov/pubmed/32346551 http://dx.doi.org/10.1016/j.omtm.2020.03.022 |
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