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A cell-based assay for the detection of neutralizing antibodies against alemtuzumab
AIM: The humanized anti-CD52 monoclonal antibody alemtuzumab depletes lymphocytes and is currently used to treat relapsing multiple sclerosis. During treatment, anti-alemtuzumab antibodies may develop and reduce effective lymphocyte depletion in future treatment cycles. RESULTS: Alemtuzumab–Alexa Fl...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Science Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177201/ https://www.ncbi.nlm.nih.gov/pubmed/32096651 http://dx.doi.org/10.2144/btn-2019-0122 |