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A Novel Highly Sensitive Method for Measuring Inflammatory Neural-Derived APC Activity in Glial Cell Lines, Mouse Brain and Human CSF
Background: Neural inflammation is linked to coagulation. Low levels of thrombin have a neuroprotective effect, mediated by activated protein C (APC). We describe a sensitive novel method for the measurement of APC activity at the low concentrations found in neural tissue. Methods: APC activity was...
Autores principales: | Golderman, Valery, Gofrit, Shany G., Maggio, Nicola, Gera, Orna, Gerasimov, Alexandra, Laks, Dar, Chapman, Joab, Shavit-Stein, Efrat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177216/ https://www.ncbi.nlm.nih.gov/pubmed/32244492 http://dx.doi.org/10.3390/ijms21072422 |
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