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Contact Allergy—Emerging Allergens and Public Health Impact

Contact allergy (sensitisation) and allergic contact dermatitis (ACD) resulting from it have a considerable public health impact. For the present review, all pertinent articles were systematically searched via Medline and Web of Science™; additionally, all available issues of the journals “Contact D...

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Autores principales: Uter, Wolfgang, Werfel, Thomas, Lepoittevin, Jean-Pierre, White, Ian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177224/
https://www.ncbi.nlm.nih.gov/pubmed/32244763
http://dx.doi.org/10.3390/ijerph17072404
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author Uter, Wolfgang
Werfel, Thomas
Lepoittevin, Jean-Pierre
White, Ian R.
author_facet Uter, Wolfgang
Werfel, Thomas
Lepoittevin, Jean-Pierre
White, Ian R.
author_sort Uter, Wolfgang
collection PubMed
description Contact allergy (sensitisation) and allergic contact dermatitis (ACD) resulting from it have a considerable public health impact. For the present review, all pertinent articles were systematically searched via Medline and Web of Science™; additionally, all available issues of the journals “Contact Dermatitis” and “Dermatitis” were manually searched, covering the years 2018–2019, thereby extending and re-focusing a previous similar review. New allergens, or previously described allergens found in a new exposure context or of other current importance, are described in sections according to substance classes, e.g., metals, preservatives, fragrances. As a common finding in many investigations, a lack of information on product composition has been noted, for instance, regarding a newly described allergen in canvas shoes (dimethylthiocarbamylbenzothiazole sulfide) and, most notably, absence of co-operation from manufacturers of glucose-monitoring devices and insulin pumps, respectively. These latter devices have been shown to cause severe ACD in a considerable number of diabetic patients caused by the liberation of isobornyl acrylate and N,N’-dimethylacrylamide, respectively, as demonstrated by an international collaboration between dermatologists and chemists. Improved and complete ingredient labelling for all types of products, and not just as we have with cosmetics at present (apart from full listing of fragrance substances) in Europe, must be put on the legislative agenda.
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spelling pubmed-71772242020-04-28 Contact Allergy—Emerging Allergens and Public Health Impact Uter, Wolfgang Werfel, Thomas Lepoittevin, Jean-Pierre White, Ian R. Int J Environ Res Public Health Review Contact allergy (sensitisation) and allergic contact dermatitis (ACD) resulting from it have a considerable public health impact. For the present review, all pertinent articles were systematically searched via Medline and Web of Science™; additionally, all available issues of the journals “Contact Dermatitis” and “Dermatitis” were manually searched, covering the years 2018–2019, thereby extending and re-focusing a previous similar review. New allergens, or previously described allergens found in a new exposure context or of other current importance, are described in sections according to substance classes, e.g., metals, preservatives, fragrances. As a common finding in many investigations, a lack of information on product composition has been noted, for instance, regarding a newly described allergen in canvas shoes (dimethylthiocarbamylbenzothiazole sulfide) and, most notably, absence of co-operation from manufacturers of glucose-monitoring devices and insulin pumps, respectively. These latter devices have been shown to cause severe ACD in a considerable number of diabetic patients caused by the liberation of isobornyl acrylate and N,N’-dimethylacrylamide, respectively, as demonstrated by an international collaboration between dermatologists and chemists. Improved and complete ingredient labelling for all types of products, and not just as we have with cosmetics at present (apart from full listing of fragrance substances) in Europe, must be put on the legislative agenda. MDPI 2020-04-01 2020-04 /pmc/articles/PMC7177224/ /pubmed/32244763 http://dx.doi.org/10.3390/ijerph17072404 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Uter, Wolfgang
Werfel, Thomas
Lepoittevin, Jean-Pierre
White, Ian R.
Contact Allergy—Emerging Allergens and Public Health Impact
title Contact Allergy—Emerging Allergens and Public Health Impact
title_full Contact Allergy—Emerging Allergens and Public Health Impact
title_fullStr Contact Allergy—Emerging Allergens and Public Health Impact
title_full_unstemmed Contact Allergy—Emerging Allergens and Public Health Impact
title_short Contact Allergy—Emerging Allergens and Public Health Impact
title_sort contact allergy—emerging allergens and public health impact
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177224/
https://www.ncbi.nlm.nih.gov/pubmed/32244763
http://dx.doi.org/10.3390/ijerph17072404
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