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Tumor Milieu Controlled by RB Tumor Suppressor

The RB gene is one of the most frequently mutated genes in human cancers. Canonically, RB exerts its tumor suppressive activity through the regulation of the G1/S transition during cell cycle progression by modulating the activity of E2F transcription factors. However, aberration of the RB gene is m...

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Detalles Bibliográficos
Autores principales: Kitajima, Shunsuke, Li, Fengkai, Takahashi, Chiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177274/
https://www.ncbi.nlm.nih.gov/pubmed/32244804
http://dx.doi.org/10.3390/ijms21072450