Cytotoxic Mechanism of Excess Polyamines Functions through Translational Repression of Specific Proteins Encoded by Polyamine Modulon

Excessive accumulation of polyamines causes cytotoxicity, including inhibition of cell growth and a decrease in viability. We investigated the mechanism of cytotoxicity caused by spermidine accumulation under various conditions using an Escherichia coli strain deficient in spermidine acetyltransfera...

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Detalles Bibliográficos
Autores principales: Sakamoto, Akihiko, Sahara, Junpei, Kawai, Gota, Yamamoto, Kaneyoshi, Ishihama, Akira, Uemura, Takeshi, Igarashi, Kazuei, Kashiwagi, Keiko, Terui, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177335/
https://www.ncbi.nlm.nih.gov/pubmed/32244348
http://dx.doi.org/10.3390/ijms21072406

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