Human iPSC modelling of a familial form of atrial fibrillation reveals a gain of function of I(f) and I(CaL) in patient-derived cardiomyocytes

AIMS: Atrial fibrillation (AF) is the most common type of cardiac arrhythmias, whose incidence is likely to increase with the aging of the population. It is considered a progressive condition, frequently observed as a complication of other cardiovascular disorders. However, recent genetic studies re...

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Detalles Bibliográficos
Autores principales: Benzoni, Patrizia, Campostrini, Giulia, Landi, Sara, Bertini, Valeria, Marchina, Eleonora, Iascone, Maria, Ahlberg, Gustav, Olesen, Morten Salling, Crescini, Elisabetta, Mora, Cristina, Bisleri, Gianluigi, Muneretto, Claudio, Ronca, Roberto, Presta, Marco, Poliani, Pier Luigi, Piovani, Giovanna, Verardi, Rosanna, Di Pasquale, Elisa, Consiglio, Antonella, Raya, Angel, Torre, Eleonora, Lodrini, Alessandra Maria, Milanesi, Raffaella, Rocchetti, Marcella, Baruscotti, Mirko, DiFrancesco, Dario, Memo, Maurizio, Barbuti, Andrea, Dell’Era, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177512/
https://www.ncbi.nlm.nih.gov/pubmed/31504264
http://dx.doi.org/10.1093/cvr/cvz217

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