Platelet Activation in Heparin-Induced Thrombocytopenia is Followed by Platelet Death via Complex Apoptotic and Non-Apoptotic Pathways

Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction characterized by thrombocytopenia and a high risk for venous or arterial thrombosis. HIT is caused by antibodies that recognize complexes of platelet factor 4 and heparin. The pathogenic mechanisms of this condition are not fully und...

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Autores principales: Mordakhanova, Elmira R., Nevzorova, Tatiana A., Synbulatova, Gulnaz E., Rauova, Lubica, Weisel, John W., Litvinov, Rustem I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177543/
https://www.ncbi.nlm.nih.gov/pubmed/32272655
http://dx.doi.org/10.3390/ijms21072556

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