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In or Out? New Insights on Exon Recognition through Splice-Site Interdependency

Noncanonical splice-site mutations are an important cause of inherited diseases. Based on in vitro and stem-cell-based studies, some splice-site variants show a stronger splice defect than expected based on their predicted effects, suggesting that other sequence motifs influence the outcome. We inve...

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Detalles Bibliográficos
Autores principales:	Khan, Mubeen, S. Cornelis, Stéphanie, Sangermano, Riccardo, J.M. Post, Iris, Janssen Groesbeek, Amber, Amsu, Jan, Gilissen, Christian, Garanto, Alejandro, W.J. Collin, Rob, P.M. Cremers, Frans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177576/ https://www.ncbi.nlm.nih.gov/pubmed/32225107 http://dx.doi.org/10.3390/ijms21072300

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