Targeted Integration of Inducible Caspase-9 in Human iPSCs Allows Efficient in vitro Clearance of iPSCs and iPSC-Macrophages

Induced pluripotent stem cells (iPSCs) offer great promise for the field of regenerative medicine, and iPSC-derived cells have already been applied in clinical practice. However, potential contamination of effector cells with residual pluripotent cells (e.g., teratoma-initiating cells) or effector c...

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Detalles Bibliográficos
Autores principales: Lipus, Alexandra, Janosz, Ewa, Ackermann, Mania, Hetzel, Miriam, Dahlke, Julia, Buchegger, Theresa, Wunderlich, Stephanie, Martin, Ulrich, Cathomen, Toni, Schambach, Axel, Moritz, Thomas, Lachmann, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177583/
https://www.ncbi.nlm.nih.gov/pubmed/32260086
http://dx.doi.org/10.3390/ijms21072481

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