Platinum(IV) Complexes of trans-1,2-diamino-4-cyclohexene: Prodrugs Affording an Oxaliplatin Analogue that Overcomes Cancer Resistance

Six platinum(IV) compounds derived from an oxaliplatin analogue containing the unsaturated cyclic diamine trans-1,2-diamino-4-cyclohexene (DACHEX), in place of the 1,2-diaminocyclohexane, and a range of axial ligands, were synthesized and characterized. The derivatives with at least one axial chlori...

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Detalles Bibliográficos
Autores principales: Papadia, Paride, Micoli, Katia, Barbanente, Alessandra, Ditaranto, Nicoletta, Hoeschele, James D., Natile, Giovanni, Marzano, Cristina, Gandin, Valentina, Margiotta, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177638/
https://www.ncbi.nlm.nih.gov/pubmed/32230896
http://dx.doi.org/10.3390/ijms21072325

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