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The Cbs Locus Affects the Expression of Senescence Markers and mtDNA Copy Number, but not Telomere Dynamics in Mice

Cystathionine β-synthase (CBS) is a housekeeping enzyme that catalyzes the first step of the homocysteine to cysteine transsulfuration pathway. Homozygous deletion of the Cbs gene in mice causes severe hyperhomocysteinemia and reduces life span. Here, we examined a possible involvement of senescence...

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Detalles Bibliográficos
Autores principales:	Utyro, Olga, Perła-Kaján, Joanna, Jakubowski, Hieronim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177707/ https://www.ncbi.nlm.nih.gov/pubmed/32260476 http://dx.doi.org/10.3390/ijms21072520

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