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Predominant Distribution of the RNAi Machinery at Apical Adherens Junctions in Colonic Epithelia Is Disrupted in Cancer

The RNA interference (RNAi) machinery is an essential component of the cell, regulating miRNA biogenesis and function. RNAi complexes were thought to localize either in the nucleus, such as the microprocessor, or in the cytoplasm, such as the RNA-induced silencing complex (RISC). We recently reveale...

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Detalles Bibliográficos
Autores principales: Nair-Menon, Joyce, Daulagala, Amanda C., Connor, Dean M., Rutledge, Lauren, Penix, Trevor, Bridges, Mary Catherine, Wellslager, Bridgette, Spyropoulos, Demetri D., Timmers, Cynthia D., Broome, Ann-Marie, Kourtidis, Antonis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177752/
https://www.ncbi.nlm.nih.gov/pubmed/32272708
http://dx.doi.org/10.3390/ijms21072559