Cargando…

Effect of Pharmacological Inhibition of the Catalytic Activity of Phosphatases of Regenerating Liver in Early T Cell Receptor Signaling Dynamics and IL-2 Production

We have previously shown the delivery of phosphatase of regenerating liver-1 (PRL-1) to the immunological synapse (IS) and proposed a regulatory role of the catalytic activity of PRLs (PRL-1, PRL-2 and PRL-3) in antigen-induced IL-2 production. Nonetheless, the expression in T cells and delivery to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aguilar-Sopeña, Oscar, Hernández-Pérez, Sara, Alegre-Gómez, Sergio, Castro-Sánchez, Patricia, Iglesias-Ceacero, Alba, Lazo, John S., Roda-Navarro, Pedro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177812/ https://www.ncbi.nlm.nih.gov/pubmed/32260565 http://dx.doi.org/10.3390/ijms21072530

Ejemplares similares

Regulation of CD4(+) T Cell Signaling and Immunological Synapse by Protein Tyrosine Phosphatases: Molecular Mechanisms in Autoimmunity
por: Castro-Sánchez, Patricia, et al.
Publicado: (2019)

Phosphatase of Regenerating Liver-1 (PRL-1) Regulates Actin Dynamics During Immunological Synapse Assembly and T Cell Effector Function
por: Castro-Sánchez, Patricia, et al.
Publicado: (2018)

Fast Diffusion Sustains Plasma Membrane Accumulation of Phosphatase of Regenerating Liver-1
por: Castro-Sánchez, Patricia, et al.
Publicado: (2020)

Bispecific Antibody Format and the Organization of Immunological Synapses in T Cell-Redirecting Strategies for Cancer Immunotherapy
por: Carrasco-Padilla, Carlos, et al.
Publicado: (2022)

The double lives of phosphatases of regenerating liver: A structural view of their catalytic and noncatalytic activities
por: Gehring, Kalle, et al.
Publicado: (2021)

Gene Expression Profiles of Human Phosphotyrosine Phosphatases Consequent to Th1 Polarisation and Effector Function
por: Castro-Sánchez, Patricia, et al.
Publicado: (2017)

Corrigendum to “Gene Expression Profiles of Human Phosphotyrosine Phosphatases Consequent to Th1 Polarisation and Effector Function”
por: Castro-Sánchez, Patricia, et al.
Publicado: (2017)

Dynamic Recruitment of Protein Tyrosine Phosphatase PTPD1 to EGF Stimulation Sites Potentiates EGFR Activation
por: Roda-Navarro, Pedro, et al.
Publicado: (2014)

Modeling catalytic promiscuity in the alkaline phosphatase superfamily
por: Duarte, Fernanda, et al.
Publicado: (2013)

Phosphatase‐independent role of phosphatase of regenerating liver in cancer progression
por: Funato, Yosuke, et al.
Publicado: (2022)

Protein Phosphatase 1 β Paralogs Encode the Zebrafish Myosin Phosphatase Catalytic Subunit
por: Jayashankar, Vaishali, et al.
Publicado: (2013)

The phosphatase of regenerating liver-3 (PRL-3) is important for IL-6-mediated survival of myeloma cells
por: Slørdahl, Tobias S., et al.
Publicado: (2016)

The Emerging Role of Protein Phosphatase in Regeneration
por: Zhang, Meiling, et al.
Publicado: (2023)

Essential Functional Interplay of the Catalytic Groups in Acid Phosphatase
por: Pfeiffer, Martin, et al.
Publicado: (2022)

Synapse topology and downmodulation events determine the functional outcome of anti-CD19 T cell-redirecting strategies
por: Ramírez-Fernández, Ángel, et al.
Publicado: (2022)

Phosphatase and Pseudo-Phosphatase Functions of Phosphatase of Regenerating Liver 3 (PRL-3) Are Insensitive to Divalent Metals In Vitro
por: Jolly, Jeffery T., et al.
Publicado: (2023)

The TriTryp Phosphatome: analysis of the protein phosphatase catalytic domains
por: Brenchley, Rachel, et al.
Publicado: (2007)

Modulation of Catalytic Activity in Multi-Domain Protein Tyrosine Phosphatases
por: Madan, Lalima L., et al.
Publicado: (2011)

The role of phosphoprotein phosphatases catalytic subunit genes in pancreatic cancer
por: Hang, Junjie, et al.
Publicado: (2021)

Targeting phosphatases of regenerating liver (PRLs) in cancer
por: Wei, Min, et al.
Publicado: (2018)

HD-PTP Is a Catalytically Inactive Tyrosine Phosphatase Due to a Conserved Divergence in Its Phosphatase Domain
por: Gingras, Marie-Claude, et al.
Publicado: (2009)

Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer
por: Lazo, John S., et al.
Publicado: (2021)

Quantum Mechanical/Molecular Mechanical Analysis of the Catalytic Mechanism of Phosphoserine Phosphatase
por: Krachtus, Dieter, et al.
Publicado: (2018)

Glycosylation Circuit Enables Improved Catalytic Properties for Recombinant Alkaline Phosphatase
por: Bozkurt, Eray Ulaş, et al.
Publicado: (2023)

Procyanidins Negatively Affect the Activity of the Phosphatases of Regenerating Liver
por: Stadlbauer, Sven, et al.
Publicado: (2015)

Regulatory mechanisms of phosphatase of regenerating liver (PRL)-3
por: Rubio, Teresa, et al.
Publicado: (2016)

WIP1 phosphatase as pharmacological target in cancer therapy
por: Pecháčková, Soňa, et al.
Publicado: (2017)

Deficiency in Tissue Non-Specific Alkaline Phosphatase Leads to Steatohepatitis in Mice Fed a High Fat Diet Similar to That Produced by a Methionine and Choline Deficient Diet
por: Gámez-Belmonte, Reyes, et al.
Publicado: (2020)

Probing the Origins of Catalytic Discrimination between Phosphate and Sulfate Monoester Hydrolysis: Comparative Analysis of Alkaline Phosphatase and Protein Tyrosine Phosphatases
por: Andrews, Logan D., et al.
Publicado: (2014)

Direct interaction between the catalytic subunit of Protein Phosphatase 1 and pRb
por: Vietri, Michele, et al.
Publicado: (2006)

Hypomethylation of the promoter of the catalytic subunit of protein phosphatase 2A in response to hyperglycemia
por: Tros, Fabiola, et al.
Publicado: (2014)

Dimerization of the voltage-sensing phosphatase controls its voltage-sensing and catalytic activity
por: Rayaprolu, Vamseedhar, et al.
Publicado: (2018)

Biophysical and functional properties of purified glucose-6-phosphatase catalytic subunit 1
por: Claxton, Derek P., et al.
Publicado: (2021)

Novel carbon nanozymes with enhanced phosphatase-like catalytic activity for antimicrobial applications
por: Nurtay, Lazzat, et al.
Publicado: (2023)

Role of phosphatase of regenerating liver 1 (PRL1) in spermatogenesis
por: Bai, Yunpeng, et al.
Publicado: (2016)

Pharmacologic epigenetic modulators of alkaline phosphatase in chronic kidney disease
por: Haarhaus, Mathias, et al.
Publicado: (2020)

Secretion and N-Linked Glycosylation Are Required for Prostatic Acid Phosphatase Catalytic and Antinociceptive Activity
por: Hurt, Julie K., et al.
Publicado: (2012)

Catalytic Signature of a Heat-Stable, Chimeric Human Alkaline Phosphatase with Therapeutic Potential
por: Kiffer-Moreira, Tina, et al.
Publicado: (2014)

Sulfation of glycosaminoglycans depends on the catalytic activity of lithium-inhibited phosphatase BPNT2 in vitro
por: Eisele, Brynna S., et al.
Publicado: (2021)

PP2A Phosphatase as a Regulator of ROS Signaling in Plants
por: Rahikainen, Moona, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_9n7q9qkud1fk76lpijmi3hi7dj