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Effect of Pharmacological Inhibition of the Catalytic Activity of Phosphatases of Regenerating Liver in Early T Cell Receptor Signaling Dynamics and IL-2 Production

We have previously shown the delivery of phosphatase of regenerating liver-1 (PRL-1) to the immunological synapse (IS) and proposed a regulatory role of the catalytic activity of PRLs (PRL-1, PRL-2 and PRL-3) in antigen-induced IL-2 production. Nonetheless, the expression in T cells and delivery to...

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Detalles Bibliográficos
Autores principales:	Aguilar-Sopeña, Oscar, Hernández-Pérez, Sara, Alegre-Gómez, Sergio, Castro-Sánchez, Patricia, Iglesias-Ceacero, Alba, Lazo, John S., Roda-Navarro, Pedro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177812/ https://www.ncbi.nlm.nih.gov/pubmed/32260565 http://dx.doi.org/10.3390/ijms21072530

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