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Sorafenib Treatment and Modulation of the Sphingolipid Pathway Affect Proliferation and Viability of Hepatocellular Carcinoma In Vitro

Hepatocellular carcinoma (HCC) shows a remarkable heterogeneity and is recognized as a chemoresistant tumor with dismal prognosis. In previous studies, we observed significant alterations in the serum sphingolipids of patients with HCC. This study aimed to investigate the in vitro effects of sorafen...

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Detalles Bibliográficos
Autores principales: Jakobi, Katja, Beyer, Sandra, Koch, Alexander, Thomas, Dominique, Schwalm, Stephanie, Zeuzem, Stefan, Pfeilschifter, Josef, Grammatikos, Georgios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177910/
https://www.ncbi.nlm.nih.gov/pubmed/32244391
http://dx.doi.org/10.3390/ijms21072409