Cargando…
Sorafenib Treatment and Modulation of the Sphingolipid Pathway Affect Proliferation and Viability of Hepatocellular Carcinoma In Vitro
Hepatocellular carcinoma (HCC) shows a remarkable heterogeneity and is recognized as a chemoresistant tumor with dismal prognosis. In previous studies, we observed significant alterations in the serum sphingolipids of patients with HCC. This study aimed to investigate the in vitro effects of sorafen...
Autores principales: | Jakobi, Katja, Beyer, Sandra, Koch, Alexander, Thomas, Dominique, Schwalm, Stephanie, Zeuzem, Stefan, Pfeilschifter, Josef, Grammatikos, Georgios |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177910/ https://www.ncbi.nlm.nih.gov/pubmed/32244391 http://dx.doi.org/10.3390/ijms21072409 |
Ejemplares similares
-
Serum sphingolipid levels associate with upcoming virologic events and HBV genotype D in a cohort of patients with HBeAg-negative HBV infection
por: Mücke, Victoria Therese, et al.
Publicado: (2018) -
Serum Sphingolipid Variations Associate with Hepatic Decompensation and Survival in Patients with Cirrhosis
por: Grammatikos, Georgios, et al.
Publicado: (2015) -
Preanalytical Biases in the Measurement of Human Blood Sphingolipids
por: Brunkhorst, Robert, et al.
Publicado: (2018) -
Low Serum Levels of (Dihydro-)Ceramides Reflect Liver Graft Dysfunction in a Real-World Cohort of Patients Post Liver Transplantation
por: Mücke, Victoria Therese, et al.
Publicado: (2018) -
Mouse Liver Compensates Loss of Sgpl1 by Secretion of Sphingolipids into Blood and Bile
por: Spohner, Anna Katharina, et al.
Publicado: (2021)