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Diet, Lifestyle and Cardiovascular Diseases: Linking Pathophysiology to Cardioprotective Effects of Natural Bioactive Compounds
Heart and blood vessels disorders comprise one of the main causes of death worldwide. Pharmacologically active natural compounds have been used as a complementary therapy in cardiovascular disease around the world in a traditional way. Dietary, natural bioactive compounds, as well as healthy lifesty...
| Autores principales: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177934/ https://www.ncbi.nlm.nih.gov/pubmed/32235611 http://dx.doi.org/10.3390/ijerph17072326 |
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| author | Sharifi-Rad, Javad Rodrigues, Célia F. Sharopov, Farukh Docea, Anca Oana Can Karaca, Aslı Sharifi-Rad, Mehdi Kahveci Karıncaoglu, Derya Gülseren, Gözde Şenol, Ezgi Demircan, Evren Taheri, Yasaman Suleria, Hafiz Ansar Rasul Özçelik, Beraat Nur Kasapoğlu, Kadriye Gültekin-Özgüven, Mine Daşkaya-Dikmen, Ceren Cho, William C. Martins, Natália Calina, Daniela |
| author_facet | Sharifi-Rad, Javad Rodrigues, Célia F. Sharopov, Farukh Docea, Anca Oana Can Karaca, Aslı Sharifi-Rad, Mehdi Kahveci Karıncaoglu, Derya Gülseren, Gözde Şenol, Ezgi Demircan, Evren Taheri, Yasaman Suleria, Hafiz Ansar Rasul Özçelik, Beraat Nur Kasapoğlu, Kadriye Gültekin-Özgüven, Mine Daşkaya-Dikmen, Ceren Cho, William C. Martins, Natália Calina, Daniela |
| author_sort | Sharifi-Rad, Javad |
| collection | PubMed |
| description | Heart and blood vessels disorders comprise one of the main causes of death worldwide. Pharmacologically active natural compounds have been used as a complementary therapy in cardiovascular disease around the world in a traditional way. Dietary, natural bioactive compounds, as well as healthy lifestyles, are considered to prevent coronary artery diseases. Pre-clinical and clinical studies reported that consumption of plant-food bioactive derivatives including polyphenolic compounds, peptides, oligosaccharides, vitamins, unsaturated fatty acids possess protective effects on cardiovascular diseases. This review aims to summarize the cardiovascular risk factors, pre-clinical studies and clinical trials related to cardioprotective properties of the plant-food-derived bioactive compounds. Molecular mechanisms by the natural bioactive compounds exert their cardiovascular protective properties have also been highlighted. |
| format | Online Article Text |
| id | pubmed-7177934 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-71779342020-04-28 Diet, Lifestyle and Cardiovascular Diseases: Linking Pathophysiology to Cardioprotective Effects of Natural Bioactive Compounds Sharifi-Rad, Javad Rodrigues, Célia F. Sharopov, Farukh Docea, Anca Oana Can Karaca, Aslı Sharifi-Rad, Mehdi Kahveci Karıncaoglu, Derya Gülseren, Gözde Şenol, Ezgi Demircan, Evren Taheri, Yasaman Suleria, Hafiz Ansar Rasul Özçelik, Beraat Nur Kasapoğlu, Kadriye Gültekin-Özgüven, Mine Daşkaya-Dikmen, Ceren Cho, William C. Martins, Natália Calina, Daniela Int J Environ Res Public Health Review Heart and blood vessels disorders comprise one of the main causes of death worldwide. Pharmacologically active natural compounds have been used as a complementary therapy in cardiovascular disease around the world in a traditional way. Dietary, natural bioactive compounds, as well as healthy lifestyles, are considered to prevent coronary artery diseases. Pre-clinical and clinical studies reported that consumption of plant-food bioactive derivatives including polyphenolic compounds, peptides, oligosaccharides, vitamins, unsaturated fatty acids possess protective effects on cardiovascular diseases. This review aims to summarize the cardiovascular risk factors, pre-clinical studies and clinical trials related to cardioprotective properties of the plant-food-derived bioactive compounds. Molecular mechanisms by the natural bioactive compounds exert their cardiovascular protective properties have also been highlighted. MDPI 2020-03-30 2020-04 /pmc/articles/PMC7177934/ /pubmed/32235611 http://dx.doi.org/10.3390/ijerph17072326 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Review Sharifi-Rad, Javad Rodrigues, Célia F. Sharopov, Farukh Docea, Anca Oana Can Karaca, Aslı Sharifi-Rad, Mehdi Kahveci Karıncaoglu, Derya Gülseren, Gözde Şenol, Ezgi Demircan, Evren Taheri, Yasaman Suleria, Hafiz Ansar Rasul Özçelik, Beraat Nur Kasapoğlu, Kadriye Gültekin-Özgüven, Mine Daşkaya-Dikmen, Ceren Cho, William C. Martins, Natália Calina, Daniela Diet, Lifestyle and Cardiovascular Diseases: Linking Pathophysiology to Cardioprotective Effects of Natural Bioactive Compounds |
| title | Diet, Lifestyle and Cardiovascular Diseases: Linking Pathophysiology to Cardioprotective Effects of Natural Bioactive Compounds |
| title_full | Diet, Lifestyle and Cardiovascular Diseases: Linking Pathophysiology to Cardioprotective Effects of Natural Bioactive Compounds |
| title_fullStr | Diet, Lifestyle and Cardiovascular Diseases: Linking Pathophysiology to Cardioprotective Effects of Natural Bioactive Compounds |
| title_full_unstemmed | Diet, Lifestyle and Cardiovascular Diseases: Linking Pathophysiology to Cardioprotective Effects of Natural Bioactive Compounds |
| title_short | Diet, Lifestyle and Cardiovascular Diseases: Linking Pathophysiology to Cardioprotective Effects of Natural Bioactive Compounds |
| title_sort | diet, lifestyle and cardiovascular diseases: linking pathophysiology to cardioprotective effects of natural bioactive compounds |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177934/ https://www.ncbi.nlm.nih.gov/pubmed/32235611 http://dx.doi.org/10.3390/ijerph17072326 |
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