The Number and Position of Orai3 Units within Heteromeric Store-Operated Ca(2+) Channels Alter the Pharmacology of I(CRAC)

Store-operated heteromeric Orai1/Orai3 channels have been discussed in the context of aging, cancer, and immune cell differentiation. In contrast to homomeric Orai1 channels, they exhibit a different pharmacology upon application of reactive oxygen species (ROS) or 2-aminoethoxydiphenyl borate (2-AP...

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Detalles Bibliográficos
Autores principales: Kappel, Sven, Kilch, Tatiana, Baur, Roland, Lochner, Martin, Peinelt, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178029/
https://www.ncbi.nlm.nih.gov/pubmed/32252254
http://dx.doi.org/10.3390/ijms21072458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178029/
https://www.ncbi.nlm.nih.gov/pubmed/32252254
http://dx.doi.org/10.3390/ijms21072458

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