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Structural Insight into the Interactions between Structurally Similar Inhibitors and SIRT6

Sirtuin 6 (SIRT6) is an NAD+-dependent deacetylase with a significant role in 20% of all cancers, such as colon cancers and rectal adenocarcinoma. However, there is currently no effective drug for cancers related to SIRT6. To explore potential inhibitors of SIRT6, it is essential to reveal details o...

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Detalles Bibliográficos
Autores principales:	Zhao, Shuang, Zhu, Yan-Yan, Wang, Xiao-Yu, Liu, Yong-Sheng, Sun, Yun-Xiang, Zhao, Qing-Jie, Li, Hui-Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178056/ https://www.ncbi.nlm.nih.gov/pubmed/32283646 http://dx.doi.org/10.3390/ijms21072601

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