Cargando…

Healthspan Maintenance and Prevention of Parkinson’s-like Phenotypes with Hydroxytyrosol and Oleuropein Aglycone in C. elegans

Numerous studies highlighted the beneficial effects of the Mediterranean diet (MD) in maintaining health, especially during ageing. Even neurodegeneration, which is part of the natural ageing process, as well as the foundation of ageing-related neurodegenerative disorders like Alzheimer’s and Parkin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brunetti, Giovanni, Di Rosa, Gabriele, Scuto, Maria, Leri, Manuela, Stefani, Massimo, Schmitz-Linneweber, Christian, Calabrese, Vittorio, Saul, Nadine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178172/ https://www.ncbi.nlm.nih.gov/pubmed/32276415 http://dx.doi.org/10.3390/ijms21072588

Ejemplares similares

Healthspan Enhancement by Olive Polyphenols in C. elegans Wild Type and Parkinson’s Models
por: Di Rosa, Gabriele, et al.
Publicado: (2020)

The Transthyretin/Oleuropein Aglycone Complex: A New Tool against TTR Amyloidosis
por: Bemporad, Francesco, et al.
Publicado: (2022)

Oleuropein aglycone stabilizes the monomeric α-synuclein and favours the growth of non-toxic aggregates
por: Palazzi, Luana, et al.
Publicado: (2018)

The Protective Role of Oleuropein Aglycone against Pesticide-Induced Toxicity in a Human Keratinocytes Cell Model
por: Leri, Manuela, et al.
Publicado: (2023)

Enhanced Healthspan in Caenorhabditis elegans Treated With Extracts From the Traditional Chinese Medicine Plants Cuscuta chinensis Lam. and Eucommia ulmoides Oliv.
por: Sayed, Shimaa M. A., et al.
Publicado: (2021)

Oleuropein Aglycone Protects Transgenic C. elegans Strains Expressing Aβ42 by Reducing Plaque Load and Motor Deficit
por: Diomede, Luisa, et al.
Publicado: (2013)

Benefit of Oleuropein Aglycone for Alzheimer's Disease by Promoting Autophagy
por: Cordero, Joaquín G., et al.
Publicado: (2018)

Effects of Oleuropein and Hydroxytyrosol on Inflammatory Mediators: Consequences on Inflammaging
por: Pojero, Fanny, et al.
Publicado: (2022)

Structure Properties, Acquisition Protocols, and Biological Activities of Oleuropein Aglycone
por: Xu, Fangxue, et al.
Publicado: (2018)

Identification of healthspan-promoting genes in Caenorhabditis elegans based on a human GWAS study
por: Saul, Nadine, et al.
Publicado: (2022)

The Polyphenol Oleuropein Aglycone Protects TgCRND8 Mice against Aß Plaque Pathology
por: Grossi, Cristina, et al.
Publicado: (2013)

Efficient 2-Step Enzymatic Cascade for the Bioconversion of Oleuropein into Hydroxytyrosol
por: Catinella, Giorgia, et al.
Publicado: (2022)

Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: a mechanistic insight
por: Rigacci, Stefania, et al.
Publicado: (2015)

Strategies to Broaden the Applications of Olive Biophenols Oleuropein and Hydroxytyrosol in Food Products
por: Monteiro, Mariana, et al.
Publicado: (2021)

Oleuropein Aglycone Protects against MAO-A-Induced Autophagy Impairment and Cardiomyocyte Death through Activation of TFEB
por: Miceli, Caterina, et al.
Publicado: (2018)

Healthy Effects of Plant Polyphenols: Molecular Mechanisms
por: Leri, Manuela, et al.
Publicado: (2020)

Enzymatic Conversion of Oleuropein to Hydroxytyrosol Using Immobilized β-Glucosidase on Porous Carbon Cuboids
por: Chatzikonstantinou, Alexandra V., et al.
Publicado: (2019)

Metabolomic and Transcriptional Profiling of Oleuropein Bioconversion into Hydroxytyrosol during Table Olive Fermentation by Lactiplantibacillus plantarum
por: Vaccalluzzo, Amanda, et al.
Publicado: (2022)

Production of Plant-Derived Oleuropein Aglycone by a Combined Membrane Process and Evaluation of Its Breast Anticancer Properties
por: Mazzei, Rosalinda, et al.
Publicado: (2020)

Potential of the Oxidized Form of the Oleuropein Aglycon to Monitor the Oil Quality Evolution of Commercial Extra-Virgin Olive Oils
por: Esposto, Sonia, et al.
Publicado: (2023)

NOTCH1: A Novel Player in the Molecular Crosstalk Underlying Articular Chondrocyte Protection by Oleuropein and Hydroxytyrosol
por: Panichi, Veronica, et al.
Publicado: (2023)

Trehalose extends healthspan in C. elegans
por: Robinson, Kristin J., et al.
Publicado: (2016)

Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. Integrase inhibition
por: Lee-Huang, Sylvia, et al.
Publicado: (2007)

Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases
por: Bulotta, Stefania, et al.
Publicado: (2014)

Role of Hydroxytyrosol and Oleuropein in the Prevention of Aging and Related Disorders: Focus on Neurodegeneration, Skeletal Muscle Dysfunction and Gut Microbiota
por: Micheli, Laura, et al.
Publicado: (2023)

Anti-Inflammatory and Antitumor Effects of Hydroxytyrosol but Not Oleuropein on Experimental Glioma In Vivo. A Putative Role for the Renin-Angiotensin System
por: Ramírez-Expósito, María Jesús, et al.
Publicado: (2018)

The Olive Biophenols Oleuropein and Hydroxytyrosol Selectively Reduce Proliferation, Influence the Cell Cycle, and Induce Apoptosis in Pancreatic Cancer Cells
por: Goldsmith, Chloe D., et al.
Publicado: (2018)

Anti-Inflammatory Effects of Nutritionally Relevant Concentrations of Oleuropein and Hydroxytyrosol on Peripheral Blood Mononuclear Cells: An Age-Related Analysis
por: Pojero, Fanny, et al.
Publicado: (2023)

Longevity interventions temporally scale healthspan in Caenorhabditis elegans
por: Statzer, Cyril, et al.
Publicado: (2022)

Olea europaea Leaf Phenolics Oleuropein, Hydroxytyrosol, Tyrosol, and Rutin Induce Apoptosis and Additionally Affect Temozolomide against Glioblastoma: In Particular, Oleuropein Inhibits Spheroid Growth by Attenuating Stem-like Cell Phenotype
por: Ercelik, Melis, et al.
Publicado: (2023)

Healthspan pathway maps in C. elegans and humans highlight transcription, proliferation/biosynthesis and lipids
por: Möller, Steffen, et al.
Publicado: (2020)

Anti-Inflammatory Effects of Olive Leaf Extract and Its Bioactive Compounds Oleacin and Oleuropein-Aglycone on Senescent Endothelial and Small Airway Epithelial Cells
por: Silvestrini, Andrea, et al.
Publicado: (2023)

Healthspan Improvements in Caenorhabditis elegans with Traditional Chinese Herbal Tea
por: Lin, Chunxiu, et al.
Publicado: (2020)

Bacterial processing of glucose modulates C. elegans lifespan and healthspan
por: Kingsley, Samuel F., et al.
Publicado: (2021)

Ginseng volatile oil prolongs the lifespan and healthspan of Caenorhabditis elegans
por: Wang, Lixin, et al.
Publicado: (2022)

Polygonati Rhizoma Polysaccharide Prolongs Lifespan and Healthspan in Caenorhabditis elegans
por: Luan, Yage, et al.
Publicado: (2023)

Hydroxytyrosol and Oleuropein-Enriched Extracts Obtained from Olive Oil Wastes and By-Products as Active Antioxidant Ingredients for Poly (Vinyl Alcohol)-Based Films
por: Luzi, Francesca, et al.
Publicado: (2021)

SERCA inhibition improves lifespan and healthspan in a chemical model of Parkinson disease in Caenorhabditis elegans
por: Romero-Sanz, Silvia, et al.
Publicado: (2023)

Exercise-Induced Mitohormesis for the Maintenance of Skeletal Muscle and Healthspan Extension
por: Musci, Robert V., et al.
Publicado: (2019)

Carnosol Improved Lifespan and Healthspan by Promoting Antioxidant Capacity in Caenorhabditis elegans
por: Lin, Chunxiu, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ui6rbmq61gu61ka45i1pp9vkjh