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Evaluation of Sibling and Twin Fragment Ions Improves the Structural Characterization of Proteins by Top-Down MALDI In-Source Decay Mass Spectrometry
[Image: see text] Comprehensive determination of primary sequence and identification of post-translational modifications (PTMs) are key elements in protein structural analysis. Various mass spectrometry (MS) based fragmentation techniques are powerful approaches for mapping both the amino acid seque...
Autores principales: | Nicolardi, Simone, Kilgour, David P. A., Dolezal, Natasja, Drijfhout, Jan W., Wuhrer, Manfred, van der Burgt, Yuri E. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178258/ https://www.ncbi.nlm.nih.gov/pubmed/32212639 http://dx.doi.org/10.1021/acs.analchem.9b05683 |
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