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Aryl Hydrocarbon Receptor Activation and Tissue Factor Induction by Fluid Shear Stress and Indoxyl Sulfate in Endothelial Cells

Endogenous agonists of the transcription factor aryl hydrocarbon receptor (AHR) such as the indolic uremic toxin, indoxyl sulfate (IS), accumulate in patients with chronic kidney disease. AHR activation by indolic toxins has prothrombotic effects on the endothelium, especially via tissue factor (TF)...

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Detalles Bibliográficos
Autores principales:	Lano, Guillaume, Laforêt, Manon, Von Kotze, Clarissa, Perrin, Justine, Addi, Tawfik, Brunet, Philippe, Poitevin, Stéphane, Burtey, Stéphane, Dou, Laetitia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178278/ https://www.ncbi.nlm.nih.gov/pubmed/32244284 http://dx.doi.org/10.3390/ijms21072392

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