Cargando…
B7-H3-Targeted CAR-T Cells Exhibit Potent Antitumor Effects on Hematologic and Solid Tumors
Recently, B7-H3 was frequently reported to be overexpressed in various cancer types and has been suggested to be a promising target for cancer immunotherapy. In the present study, we analyzed the mRNA expression of B7-H3 in The Cancer Genome Atlas (TCGA) database and validated its expression across...
Autores principales: | Zhang, Zongliang, Jiang, Caiying, Liu, Zhiyong, Yang, Meijia, Tang, Xin, Wang, Yuelong, Zheng, Meijun, Huang, Jianhan, Zhong, Kunhong, Zhao, Shasha, Tang, Mei, Zhou, Tingyue, Yang, Hui, Guo, Gang, Zhou, Liangxue, Xu, Jianguo, Tong, Aiping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178328/ https://www.ncbi.nlm.nih.gov/pubmed/32346608 http://dx.doi.org/10.1016/j.omto.2020.03.019 |
Ejemplares similares
-
Tandem CAR-T cells targeting CD70 and B7-H3 exhibit potent preclinical activity against multiple solid tumors
por: Yang, Meijia, et al.
Publicado: (2020) -
Fn14-targeted BiTE and CAR-T cells demonstrate potent preclinical activity against glioblastoma
por: Li, Gaowei, et al.
Publicado: (2021) -
B7-H3 as a Novel CAR-T Therapeutic Target for Glioblastoma
por: Tang, Xin, et al.
Publicado: (2019) -
Bioactivity and safety of B7‐H3‐targeted chimeric antigen receptor T cells against anaplastic meningioma
por: Tang, Xin, et al.
Publicado: (2020) -
AP-64, Encoded by C5orf46, Exhibits Antimicrobial Activity against Gram-Negative Bacteria
por: Zhong, Kunhong, et al.
Publicado: (2021)