Cargando…
Changes in the Rhythm of Speech Difference between People with Nondegenerative Mild Cognitive Impairment and with Preclinical Dementia
This study explores several speech parameters related to mild cognitive impairment, as well as those that might be flagging the presence of an underlying neurodegenerative process. Speech is an excellent biomarker because it is not invasive and, what is more, its analysis is rapid and economical. Ou...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178534/ https://www.ncbi.nlm.nih.gov/pubmed/32351632 http://dx.doi.org/10.1155/2020/4683573 |
_version_ | 1783525476958994432 |
---|---|
author | Meilán, Juan J. G. Martínez-Sánchez, Francisco Martínez-Nicolás, Israel Llorente, Thide E. Carro, Juan |
author_facet | Meilán, Juan J. G. Martínez-Sánchez, Francisco Martínez-Nicolás, Israel Llorente, Thide E. Carro, Juan |
author_sort | Meilán, Juan J. G. |
collection | PubMed |
description | This study explores several speech parameters related to mild cognitive impairment, as well as those that might be flagging the presence of an underlying neurodegenerative process. Speech is an excellent biomarker because it is not invasive and, what is more, its analysis is rapid and economical. Our aim has been to ascertain whether the typical speech patterns of people with Alzheimer's disease are also present during the disorder's preclinical stages. To do so, we shall be using a task that involves reading out aloud. This is followed by an analysis of the recordings, looking for the possible parameters differentiating between those older people with MCI and a high probability of developing dementia and those with MCI that will not do so. We found that the disease's most differentiating parameters prior to its onset involve changes in speech duration and an alteration in rhythm rate and intensity. These parameters seem to be related to the first difficulties in lexical access among older people with AD. |
format | Online Article Text |
id | pubmed-7178534 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-71785342020-04-29 Changes in the Rhythm of Speech Difference between People with Nondegenerative Mild Cognitive Impairment and with Preclinical Dementia Meilán, Juan J. G. Martínez-Sánchez, Francisco Martínez-Nicolás, Israel Llorente, Thide E. Carro, Juan Behav Neurol Research Article This study explores several speech parameters related to mild cognitive impairment, as well as those that might be flagging the presence of an underlying neurodegenerative process. Speech is an excellent biomarker because it is not invasive and, what is more, its analysis is rapid and economical. Our aim has been to ascertain whether the typical speech patterns of people with Alzheimer's disease are also present during the disorder's preclinical stages. To do so, we shall be using a task that involves reading out aloud. This is followed by an analysis of the recordings, looking for the possible parameters differentiating between those older people with MCI and a high probability of developing dementia and those with MCI that will not do so. We found that the disease's most differentiating parameters prior to its onset involve changes in speech duration and an alteration in rhythm rate and intensity. These parameters seem to be related to the first difficulties in lexical access among older people with AD. Hindawi 2020-04-14 /pmc/articles/PMC7178534/ /pubmed/32351632 http://dx.doi.org/10.1155/2020/4683573 Text en Copyright © 2020 Juan J. G. Meilán et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Meilán, Juan J. G. Martínez-Sánchez, Francisco Martínez-Nicolás, Israel Llorente, Thide E. Carro, Juan Changes in the Rhythm of Speech Difference between People with Nondegenerative Mild Cognitive Impairment and with Preclinical Dementia |
title | Changes in the Rhythm of Speech Difference between People with Nondegenerative Mild Cognitive Impairment and with Preclinical Dementia |
title_full | Changes in the Rhythm of Speech Difference between People with Nondegenerative Mild Cognitive Impairment and with Preclinical Dementia |
title_fullStr | Changes in the Rhythm of Speech Difference between People with Nondegenerative Mild Cognitive Impairment and with Preclinical Dementia |
title_full_unstemmed | Changes in the Rhythm of Speech Difference between People with Nondegenerative Mild Cognitive Impairment and with Preclinical Dementia |
title_short | Changes in the Rhythm of Speech Difference between People with Nondegenerative Mild Cognitive Impairment and with Preclinical Dementia |
title_sort | changes in the rhythm of speech difference between people with nondegenerative mild cognitive impairment and with preclinical dementia |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178534/ https://www.ncbi.nlm.nih.gov/pubmed/32351632 http://dx.doi.org/10.1155/2020/4683573 |
work_keys_str_mv | AT meilanjuanjg changesintherhythmofspeechdifferencebetweenpeoplewithnondegenerativemildcognitiveimpairmentandwithpreclinicaldementia AT martinezsanchezfrancisco changesintherhythmofspeechdifferencebetweenpeoplewithnondegenerativemildcognitiveimpairmentandwithpreclinicaldementia AT martineznicolasisrael changesintherhythmofspeechdifferencebetweenpeoplewithnondegenerativemildcognitiveimpairmentandwithpreclinicaldementia AT llorentethidee changesintherhythmofspeechdifferencebetweenpeoplewithnondegenerativemildcognitiveimpairmentandwithpreclinicaldementia AT carrojuan changesintherhythmofspeechdifferencebetweenpeoplewithnondegenerativemildcognitiveimpairmentandwithpreclinicaldementia |