Cargando…

Superoxide Dismutase Mimic, MnTE-2-PyP Enhances Rectal Anastomotic Strength in Rats after Preoperative Chemoradiotherapy

BACKGROUND: Rectal cancer is one of the malignant diseases with high morbidity and mortality in the world. Currently, surgical resection is the main treatment method, and preoperative chemoradiotherapy (CRT) is widely used in clinical application to increase resectability and decrease the local recu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Yu, Wang, Qi, Luo, Jiajun, Jiang, Yue, Zhou, Rui, Tong, Shilun, Wang, Zhihua, Tong, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178539/ https://www.ncbi.nlm.nih.gov/pubmed/32351671 http://dx.doi.org/10.1155/2020/3509859

Ejemplares similares

Superoxide dismutase mimic, MnTE-2-PyP(5+) ameliorates acute and chronic proctitis following focal proton irradiation of the rat rectum()
por: Archambeau, John O., et al.
Publicado: (2013)

Antioxidant Effect of MnTE-2-PyP on Lung in Asthma Mice Model
por: Terziev, Lyudmil, et al.
Publicado: (2012)

The SOD Mimic, MnTE-2-PyP, Protects from Chronic Fibrosis and Inflammation in Irradiated Normal Pelvic Tissues
por: Shrishrimal, Shashank, et al.
Publicado: (2017)

MnTE-2-PyP protects fibroblast mitochondria from hyperglycemia and radiation exposure
por: Chatterjee, Arpita, et al.
Publicado: (2022)

The Antioxidant, MnTE-2-PyP, Prevents Side-Effects Incurred by Prostate Cancer Irradiation
por: Oberley-Deegan, Rebecca E., et al.
Publicado: (2012)

Nanoformulation of the superoxide dismutase mimic, MnTnBuOE-2-PyP(5+), prevents its acute hypotensive response
por: Schlichte, Sarah L., et al.
Publicado: (2020)

MnTE-2-PyP Attenuates TGF-β-Induced Epithelial-Mesenchymal Transition of Colorectal Cancer Cells by Inhibiting the Smad2/3 Signaling Pathway
por: Yang, Yu, et al.
Publicado: (2019)

The Metalloporphyrin Antioxidant, MnTE-2-PyP, Inhibits Th2 Cell Immune Responses in an Asthma Model
por: Jungsuwadee, Paiboon, et al.
Publicado: (2012)

MnTE-2-PyP Suppresses Prostate Cancer Cell Growth via H(2)O(2) Production
por: Zhu, Yuxiang, et al.
Publicado: (2020)

CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP(5+)
por: Leu, David, et al.
Publicado: (2017)

Redox-Active Drug, MnTE-2-PyP(5+), Prevents and Treats Cardiac Arrhythmias Preserving Heart Contractile Function
por: Barbosa, Andrezza M., et al.
Publicado: (2020)

MnTE-2-PyP, a manganese porphyrin, reduces cytotoxicity caused by irradiation in a diabetic environment through the induction of endogenous antioxidant defenses
por: Chatterjee, Arpita, et al.
Publicado: (2020)

Mn(III) Porphyrin, MnTnBuOE-2-PyP(5+), Commonly Known as a Mimic of Superoxide Dismutase Enzyme, Protects Cardiomyocytes from Hypoxia/Reoxygenation Induced Injury via Reducing Oxidative Stress
por: Sharma, Sudha, et al.
Publicado: (2023)

Thermal Stability Kinetics and Shelf Life Estimation of the Redox-Active Therapeutic and Mimic of Superoxide Dismutase Enzyme, Mn(III) meso-Tetrakis(N-ethylpyridinium-2-yl)porphyrin Chloride (MnTE-2-PyPCl(5), BMX-010)
por: Maia, Clarissa G. C., et al.
Publicado: (2021)

Post-Irradiation Treatment with a Superoxide Dismutase Mimic, MnTnHex-2-PyP(5+), Mitigates Radiation Injury in the Lungs of Non-Human Primates after Whole-Thorax Exposure to Ionizing Radiation
por: Cline, John Mark, et al.
Publicado: (2018)

The SOD Mimic MnTnHex-2-PyP(5+) Reduces the Viability and Migration of 786-O Human Renal Cancer Cells
por: Costa, João G., et al.
Publicado: (2019)

Fe Porphyrin-Based SOD Mimic and Redox-Active Compound, (OH)FeTnHex-2-PyP(4+), in a Rodent Ischemic Stroke (MCAO) Model: Efficacy and Pharmacokinetics as Compared to Its Mn Analogue, (H(2)O)MnTnHex-2-PyP(5+)
por: Li, Litao, et al.
Publicado: (2020)

Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP(5+)()
por: Gauter-Fleckenstein, Benjamin, et al.
Publicado: (2014)

Scavenging of Superoxide in Aprotic Solvents of Four Isoflavones That Mimic Superoxide Dismutase
por: Yu, Sandra, et al.
Publicado: (2023)

Reversible displacive transformation in MnTe polymorphic semiconductor
por: Mori, Shunsuke, et al.
Publicado: (2020)

Cupric Yersiniabactin Is a Virulence-Associated Superoxide Dismutase Mimic
por: Chaturvedi, Kaveri S., et al.
Publicado: (2013)

Porphyrin‐Based SOD Mimic MnTnBuOE‐2‐PyP(5+) Inhibits Mechanisms of Aortic Valve Remodeling in Human and Murine Models of Aortic Valve Sclerosis
por: Anselmo, Wanda, et al.
Publicado: (2018)

Multiple-stable anisotropic magnetoresistance memory in antiferromagnetic MnTe
por: Kriegner, D., et al.
Publicado: (2016)

A Redox-active Mn Porphyrin, MnTnBuOE-2-PyP(5+), Synergizes with Carboplatin in Treatment of Chemoresistant Ovarian Cell Line
por: Chaiswing, Luksana, et al.
Publicado: (2022)

SODa: An Mn/Fe superoxide dismutase prediction and design server
por: Kwasigroch, Jean Marc, et al.
Publicado: (2008)

Orally available Mn porphyrins with superoxide dismutase and catalase activities
por: Rosenthal, Rosalind A., et al.
Publicado: (2009)

MnTnBuOE-2-PyP protects normal colorectal fibroblasts from radiation damage and simultaneously enhances radio/chemotherapeutic killing of colorectal cancer cells
por: Kosmacek, Elizabeth A., et al.
Publicado: (2016)

Rational Design of Superoxide Dismutase (SOD) Mimics: The Evaluation of the Therapeutic Potential of New Cationic Mn Porphyrins with Linear and Cyclic Substituents
por: Tovmasyan, Artak, et al.
Publicado: (2014)

Inertness of Superoxide Dismutase Mimics Mn(II) Complexes Based on an Open-Chain Ligand, Bioactivity, and Detection in Intestinal Epithelial Cells
por: Schanne, Gabrielle, et al.
Publicado: (2022)

Superoxide Dismutases and Superoxide Reductases
por: Sheng, Yuewei, et al.
Publicado: (2014)

Characterization of ancestral Fe/Mn superoxide dismutases indicates their cambialistic origin
por: Valenti, Rosario, et al.
Publicado: (2022)

Paramagnon drag in high thermoelectric figure of merit Li-doped MnTe
por: Zheng, Y., et al.
Publicado: (2019)

A novel redox regulator, MnTnBuOE-2-PyP(5+), enhances normal hematopoietic stem/progenitor cell function
por: Zhao, Y., et al.
Publicado: (2017)

MnTnHex-2-PyP(5+) Displays Anticancer Properties and Enhances Cisplatin Effects in Non-Small Cell Lung Cancer Cells
por: Soares, Rita B., et al.
Publicado: (2022)

A New Mixed-Valence Mn(II)Mn(III) Compound With Catalase and Superoxide Dismutase Activities
por: Costa, Rafael O., et al.
Publicado: (2018)

MnTnBuOE-2-PyP treatment protects from radioactive iodine (I-131) treatment-related side effects in thyroid cancer
por: Patel, Anery, et al.
Publicado: (2019)

Assessing the Effects of Redox Modifier MnTnBuOE-2-PyP 5+ on Cognition and Hippocampal Physiology Following Doxorubicin, Cyclophosphamide, and Paclitaxel Treatment
por: McElroy, Taylor, et al.
Publicado: (2020)

Expression of Mn-Superoxide Dismutase Gene in Nontumorigenic and Tumorigenic Human Mammary Epithelial Cells
por: Mukhopadhyay, Sutapa, et al.
Publicado: (2004)

Paradoxical Relationship between Mn Superoxide Dismutase Deficiency and Radiation-Induced Cognitive Defects
por: Corniola, Rikki, et al.
Publicado: (2012)

Immunohistochemical assessment of mitochondrial superoxide dismutase (MnSOD) in colorectal premalignant and malignant lesions
por: Piecuch, Adam, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_7f77mh049etrm2j8opqe8cs7lj