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Antimalarial combination therapies increase gastric ulcers through an imbalance of basic antioxidative-oxidative enzymes in male Wistar rats
OBJECTIVE: Antimalarials are globally used against plasmodium infections, however, information on the safety of new antimalarial combination therapies on the gastric mucosa is scarce. The aim of this study was to investigate the effects of Artesunate-Amodiaquine and Artemether-Lumefantrine on ulcer...
Autores principales: | Kalange, Muhamudu, Nansunga, Miriam, Kasozi, Keneth Iceland, Kasolo, Josephine, Namulema, Jackline, Atusiimirwe, Jovile Kasande, Ayikobua, Emanuel Tiyo, Ssempijja, Fred, Munanura, Edson Ireeta, Matama, Kevin, Semuyaba, Ibrahim, Zirintunda, Gerald, Okpanachi, Alfred Omachonu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178572/ https://www.ncbi.nlm.nih.gov/pubmed/32326975 http://dx.doi.org/10.1186/s13104-020-05073-7 |
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