Cargando…

Mitral valve replacement in mitral stenosis; the problem of small left ventricle

BACKGROUND: Mitral valve stenosis in adults especially due to rheumatic heart disease may be associated with a smaller than normal left ventricular cavity. Mitral valve replacement in such cases may lead to hemodynamic instability either during weaning from cardiopulmonary bypass or in the early pos...

Descripción completa

Detalles Bibliográficos
Autores principales: Alkady, Hesham, Saber, Ahmed, Abouramadan, Sobhy, Elnaggar, Ahmed, Nasr, Sherif, Mahmoud, Eman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178577/
https://www.ncbi.nlm.nih.gov/pubmed/32321541
http://dx.doi.org/10.1186/s13019-020-01108-z
_version_ 1783525487338848256
author Alkady, Hesham
Saber, Ahmed
Abouramadan, Sobhy
Elnaggar, Ahmed
Nasr, Sherif
Mahmoud, Eman
author_facet Alkady, Hesham
Saber, Ahmed
Abouramadan, Sobhy
Elnaggar, Ahmed
Nasr, Sherif
Mahmoud, Eman
author_sort Alkady, Hesham
collection PubMed
description BACKGROUND: Mitral valve stenosis in adults especially due to rheumatic heart disease may be associated with a smaller than normal left ventricular cavity. Mitral valve replacement in such cases may lead to hemodynamic instability either during weaning from cardiopulmonary bypass or in the early postoperative period manifested by the need for inotropic support and even mortality due to low cardiac output syndrome. PATIENTS AND METHODS: 184 patients with predominately severe stenotic mitral valves who underwent elective isolated mitral valve replacement in the period between January 2012 and January 2018 at our hospital were included in this study. Patients were divided into 2 matched groups; (small LV group) consisting of 86 cases and (normal or dilated LV group) consisting of 98 cases. RESULTS: There were no statistically significant differences in operative details among both groups apart from the need for inotropic support and intra-aortic balloon pump due to low cardiac output which were statistically significantly higher in (small LV group) than (normal or dilated LV group) with a p-values of 0.01 and 0.03 respectively. Within the ICU stay only the incidence of occurrence of heart failure was significantly higher in (small LV group) with a p-value of 0.008. No statistically significant difference could be elicited in the in-hospital mortality between both groups (p-value = 0.1). CONCLUSION: Patients with mitral valve stenosis and small left ventricular cavity are in a higher need for inotropic and even mechanical support after mitral valve replacement as well as at a higher risk for the development of heart failure before hospital discharge than patients with mitral stenosis and normal-sized left ventricular cavity.
format Online
Article
Text
id pubmed-7178577
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-71785772020-04-24 Mitral valve replacement in mitral stenosis; the problem of small left ventricle Alkady, Hesham Saber, Ahmed Abouramadan, Sobhy Elnaggar, Ahmed Nasr, Sherif Mahmoud, Eman J Cardiothorac Surg Research Article BACKGROUND: Mitral valve stenosis in adults especially due to rheumatic heart disease may be associated with a smaller than normal left ventricular cavity. Mitral valve replacement in such cases may lead to hemodynamic instability either during weaning from cardiopulmonary bypass or in the early postoperative period manifested by the need for inotropic support and even mortality due to low cardiac output syndrome. PATIENTS AND METHODS: 184 patients with predominately severe stenotic mitral valves who underwent elective isolated mitral valve replacement in the period between January 2012 and January 2018 at our hospital were included in this study. Patients were divided into 2 matched groups; (small LV group) consisting of 86 cases and (normal or dilated LV group) consisting of 98 cases. RESULTS: There were no statistically significant differences in operative details among both groups apart from the need for inotropic support and intra-aortic balloon pump due to low cardiac output which were statistically significantly higher in (small LV group) than (normal or dilated LV group) with a p-values of 0.01 and 0.03 respectively. Within the ICU stay only the incidence of occurrence of heart failure was significantly higher in (small LV group) with a p-value of 0.008. No statistically significant difference could be elicited in the in-hospital mortality between both groups (p-value = 0.1). CONCLUSION: Patients with mitral valve stenosis and small left ventricular cavity are in a higher need for inotropic and even mechanical support after mitral valve replacement as well as at a higher risk for the development of heart failure before hospital discharge than patients with mitral stenosis and normal-sized left ventricular cavity. BioMed Central 2020-04-22 /pmc/articles/PMC7178577/ /pubmed/32321541 http://dx.doi.org/10.1186/s13019-020-01108-z Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Alkady, Hesham
Saber, Ahmed
Abouramadan, Sobhy
Elnaggar, Ahmed
Nasr, Sherif
Mahmoud, Eman
Mitral valve replacement in mitral stenosis; the problem of small left ventricle
title Mitral valve replacement in mitral stenosis; the problem of small left ventricle
title_full Mitral valve replacement in mitral stenosis; the problem of small left ventricle
title_fullStr Mitral valve replacement in mitral stenosis; the problem of small left ventricle
title_full_unstemmed Mitral valve replacement in mitral stenosis; the problem of small left ventricle
title_short Mitral valve replacement in mitral stenosis; the problem of small left ventricle
title_sort mitral valve replacement in mitral stenosis; the problem of small left ventricle
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178577/
https://www.ncbi.nlm.nih.gov/pubmed/32321541
http://dx.doi.org/10.1186/s13019-020-01108-z
work_keys_str_mv AT alkadyhesham mitralvalvereplacementinmitralstenosistheproblemofsmallleftventricle
AT saberahmed mitralvalvereplacementinmitralstenosistheproblemofsmallleftventricle
AT abouramadansobhy mitralvalvereplacementinmitralstenosistheproblemofsmallleftventricle
AT elnaggarahmed mitralvalvereplacementinmitralstenosistheproblemofsmallleftventricle
AT nasrsherif mitralvalvereplacementinmitralstenosistheproblemofsmallleftventricle
AT mahmoudeman mitralvalvereplacementinmitralstenosistheproblemofsmallleftventricle