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Mitral valve replacement in mitral stenosis; the problem of small left ventricle
BACKGROUND: Mitral valve stenosis in adults especially due to rheumatic heart disease may be associated with a smaller than normal left ventricular cavity. Mitral valve replacement in such cases may lead to hemodynamic instability either during weaning from cardiopulmonary bypass or in the early pos...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178577/ https://www.ncbi.nlm.nih.gov/pubmed/32321541 http://dx.doi.org/10.1186/s13019-020-01108-z |
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author | Alkady, Hesham Saber, Ahmed Abouramadan, Sobhy Elnaggar, Ahmed Nasr, Sherif Mahmoud, Eman |
author_facet | Alkady, Hesham Saber, Ahmed Abouramadan, Sobhy Elnaggar, Ahmed Nasr, Sherif Mahmoud, Eman |
author_sort | Alkady, Hesham |
collection | PubMed |
description | BACKGROUND: Mitral valve stenosis in adults especially due to rheumatic heart disease may be associated with a smaller than normal left ventricular cavity. Mitral valve replacement in such cases may lead to hemodynamic instability either during weaning from cardiopulmonary bypass or in the early postoperative period manifested by the need for inotropic support and even mortality due to low cardiac output syndrome. PATIENTS AND METHODS: 184 patients with predominately severe stenotic mitral valves who underwent elective isolated mitral valve replacement in the period between January 2012 and January 2018 at our hospital were included in this study. Patients were divided into 2 matched groups; (small LV group) consisting of 86 cases and (normal or dilated LV group) consisting of 98 cases. RESULTS: There were no statistically significant differences in operative details among both groups apart from the need for inotropic support and intra-aortic balloon pump due to low cardiac output which were statistically significantly higher in (small LV group) than (normal or dilated LV group) with a p-values of 0.01 and 0.03 respectively. Within the ICU stay only the incidence of occurrence of heart failure was significantly higher in (small LV group) with a p-value of 0.008. No statistically significant difference could be elicited in the in-hospital mortality between both groups (p-value = 0.1). CONCLUSION: Patients with mitral valve stenosis and small left ventricular cavity are in a higher need for inotropic and even mechanical support after mitral valve replacement as well as at a higher risk for the development of heart failure before hospital discharge than patients with mitral stenosis and normal-sized left ventricular cavity. |
format | Online Article Text |
id | pubmed-7178577 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-71785772020-04-24 Mitral valve replacement in mitral stenosis; the problem of small left ventricle Alkady, Hesham Saber, Ahmed Abouramadan, Sobhy Elnaggar, Ahmed Nasr, Sherif Mahmoud, Eman J Cardiothorac Surg Research Article BACKGROUND: Mitral valve stenosis in adults especially due to rheumatic heart disease may be associated with a smaller than normal left ventricular cavity. Mitral valve replacement in such cases may lead to hemodynamic instability either during weaning from cardiopulmonary bypass or in the early postoperative period manifested by the need for inotropic support and even mortality due to low cardiac output syndrome. PATIENTS AND METHODS: 184 patients with predominately severe stenotic mitral valves who underwent elective isolated mitral valve replacement in the period between January 2012 and January 2018 at our hospital were included in this study. Patients were divided into 2 matched groups; (small LV group) consisting of 86 cases and (normal or dilated LV group) consisting of 98 cases. RESULTS: There were no statistically significant differences in operative details among both groups apart from the need for inotropic support and intra-aortic balloon pump due to low cardiac output which were statistically significantly higher in (small LV group) than (normal or dilated LV group) with a p-values of 0.01 and 0.03 respectively. Within the ICU stay only the incidence of occurrence of heart failure was significantly higher in (small LV group) with a p-value of 0.008. No statistically significant difference could be elicited in the in-hospital mortality between both groups (p-value = 0.1). CONCLUSION: Patients with mitral valve stenosis and small left ventricular cavity are in a higher need for inotropic and even mechanical support after mitral valve replacement as well as at a higher risk for the development of heart failure before hospital discharge than patients with mitral stenosis and normal-sized left ventricular cavity. BioMed Central 2020-04-22 /pmc/articles/PMC7178577/ /pubmed/32321541 http://dx.doi.org/10.1186/s13019-020-01108-z Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Alkady, Hesham Saber, Ahmed Abouramadan, Sobhy Elnaggar, Ahmed Nasr, Sherif Mahmoud, Eman Mitral valve replacement in mitral stenosis; the problem of small left ventricle |
title | Mitral valve replacement in mitral stenosis; the problem of small left ventricle |
title_full | Mitral valve replacement in mitral stenosis; the problem of small left ventricle |
title_fullStr | Mitral valve replacement in mitral stenosis; the problem of small left ventricle |
title_full_unstemmed | Mitral valve replacement in mitral stenosis; the problem of small left ventricle |
title_short | Mitral valve replacement in mitral stenosis; the problem of small left ventricle |
title_sort | mitral valve replacement in mitral stenosis; the problem of small left ventricle |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178577/ https://www.ncbi.nlm.nih.gov/pubmed/32321541 http://dx.doi.org/10.1186/s13019-020-01108-z |
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