Nucleus size and DNA accessibility are linked to the regulation of paraspeckle formation in cellular differentiation

BACKGROUND: Many long noncoding RNAs (lncRNAs) have been implicated in general and cell type-specific molecular regulation. Here, we asked what underlies the fundamental basis for the seemingly random appearance of nuclear lncRNA condensates in cells, and we sought compounds that can promote the dis...

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Detalles Bibliográficos
Autores principales: Grosch, Markus, Ittermann, Sebastian, Rusha, Ejona, Greisle, Tobias, Ori, Chaido, Truong, Dong-Jiunn Jeffery, O’Neill, Adam C., Pertek, Anna, Westmeyer, Gil Gregor, Drukker, Micha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178590/
https://www.ncbi.nlm.nih.gov/pubmed/32321486
http://dx.doi.org/10.1186/s12915-020-00770-y

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