Macrophage M2 polarization induced by exosomes from adipose-derived stem cells contributes to the exosomal proangiogenic effect on mouse ischemic hindlimb

BACKGROUND: M2 macrophages and exosomes from adipose-derived stem cells (ASCs) are both reported to promote angiogenesis. However, the possible synergistic effects between exogenous exosomes and endogenous M2 macrophages are poorly understood. METHODS: Exosomes were isolated from conditioned medium...

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Detalles Bibliográficos
Autores principales: Zhu, Dihan, Johnson, Takerra K., Wang, Yang, Thomas, Miracle, Huynh, Ky, Yang, Qinglin, Bond, Vincent C., Chen, Y. Eugene, Liu, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178595/
https://www.ncbi.nlm.nih.gov/pubmed/32321589
http://dx.doi.org/10.1186/s13287-020-01669-9

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