Alantolactone suppresses inflammation, apoptosis and oxidative stress in cigarette smoke-induced human bronchial epithelial cells through activation of Nrf2/HO-1 and inhibition of the NF-κB pathways

BACKGROUND: It is well established that airway remodeling and inflammation are characteristics for chronic obstructive pulmonary disease (COPD). Moreover, cigarette smoke extract (CSE) promots inflammation, apoptosis and oxidative stress in COPD. And, there is evidence suggested that alantolactone (...

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Detalles Bibliográficos
Autores principales: Dang, Xiaomin, He, Beibei, Ning, Qian, Liu, Ya, Guo, Jianxin, Niu, Gang, Chen, Mingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178609/
https://www.ncbi.nlm.nih.gov/pubmed/32321531
http://dx.doi.org/10.1186/s12931-020-01358-4

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