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Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections

Infection represents one of the major risk factors in persistent and difficult to treat wounds. This study focuses on developing antimicrobial wound dressings coated with silver nanoparticles, sodium alginate and different essential oils, to avoid wound infection and biofilm formation. The design of...

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Autores principales: Vasile, Bogdan Stefan, Birca, Alexandra Catalina, Musat, Mihaela Carmen, Holban, Alina Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178656/
https://www.ncbi.nlm.nih.gov/pubmed/32260273
http://dx.doi.org/10.3390/ma13071682
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author Vasile, Bogdan Stefan
Birca, Alexandra Catalina
Musat, Mihaela Carmen
Holban, Alina Maria
author_facet Vasile, Bogdan Stefan
Birca, Alexandra Catalina
Musat, Mihaela Carmen
Holban, Alina Maria
author_sort Vasile, Bogdan Stefan
collection PubMed
description Infection represents one of the major risk factors in persistent and difficult to treat wounds. This study focuses on developing antimicrobial wound dressings coated with silver nanoparticles, sodium alginate and different essential oils, to avoid wound infection and biofilm formation. The design of the wound dressings was done by the dip coating method. The characteristics of the developed materials were analysed by physicochemical (FT-IR, XRD, SEM, TEM) and biological (antimicrobial tests) approaches. The results demonstrated uniform silver nanoparticle formation on the substrate, and the developed nanomodified dressings were proven to have increased antimicrobial and antibiofilm potential. The developed wound dressings based on silver nanoparticles, sodium alginate and essential oils have real potential in treating infections, and can be investigated as an efficient alternative to antibiotics and topical preparations for wound management.
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spelling pubmed-71786562020-04-28 Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections Vasile, Bogdan Stefan Birca, Alexandra Catalina Musat, Mihaela Carmen Holban, Alina Maria Materials (Basel) Article Infection represents one of the major risk factors in persistent and difficult to treat wounds. This study focuses on developing antimicrobial wound dressings coated with silver nanoparticles, sodium alginate and different essential oils, to avoid wound infection and biofilm formation. The design of the wound dressings was done by the dip coating method. The characteristics of the developed materials were analysed by physicochemical (FT-IR, XRD, SEM, TEM) and biological (antimicrobial tests) approaches. The results demonstrated uniform silver nanoparticle formation on the substrate, and the developed nanomodified dressings were proven to have increased antimicrobial and antibiofilm potential. The developed wound dressings based on silver nanoparticles, sodium alginate and essential oils have real potential in treating infections, and can be investigated as an efficient alternative to antibiotics and topical preparations for wound management. MDPI 2020-04-03 /pmc/articles/PMC7178656/ /pubmed/32260273 http://dx.doi.org/10.3390/ma13071682 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Vasile, Bogdan Stefan
Birca, Alexandra Catalina
Musat, Mihaela Carmen
Holban, Alina Maria
Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections
title Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections
title_full Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections
title_fullStr Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections
title_full_unstemmed Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections
title_short Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections
title_sort wound dressings coated with silver nanoparticles and essential oils for the management of wound infections
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178656/
https://www.ncbi.nlm.nih.gov/pubmed/32260273
http://dx.doi.org/10.3390/ma13071682
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