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Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections
Infection represents one of the major risk factors in persistent and difficult to treat wounds. This study focuses on developing antimicrobial wound dressings coated with silver nanoparticles, sodium alginate and different essential oils, to avoid wound infection and biofilm formation. The design of...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178656/ https://www.ncbi.nlm.nih.gov/pubmed/32260273 http://dx.doi.org/10.3390/ma13071682 |
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author | Vasile, Bogdan Stefan Birca, Alexandra Catalina Musat, Mihaela Carmen Holban, Alina Maria |
author_facet | Vasile, Bogdan Stefan Birca, Alexandra Catalina Musat, Mihaela Carmen Holban, Alina Maria |
author_sort | Vasile, Bogdan Stefan |
collection | PubMed |
description | Infection represents one of the major risk factors in persistent and difficult to treat wounds. This study focuses on developing antimicrobial wound dressings coated with silver nanoparticles, sodium alginate and different essential oils, to avoid wound infection and biofilm formation. The design of the wound dressings was done by the dip coating method. The characteristics of the developed materials were analysed by physicochemical (FT-IR, XRD, SEM, TEM) and biological (antimicrobial tests) approaches. The results demonstrated uniform silver nanoparticle formation on the substrate, and the developed nanomodified dressings were proven to have increased antimicrobial and antibiofilm potential. The developed wound dressings based on silver nanoparticles, sodium alginate and essential oils have real potential in treating infections, and can be investigated as an efficient alternative to antibiotics and topical preparations for wound management. |
format | Online Article Text |
id | pubmed-7178656 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-71786562020-04-28 Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections Vasile, Bogdan Stefan Birca, Alexandra Catalina Musat, Mihaela Carmen Holban, Alina Maria Materials (Basel) Article Infection represents one of the major risk factors in persistent and difficult to treat wounds. This study focuses on developing antimicrobial wound dressings coated with silver nanoparticles, sodium alginate and different essential oils, to avoid wound infection and biofilm formation. The design of the wound dressings was done by the dip coating method. The characteristics of the developed materials were analysed by physicochemical (FT-IR, XRD, SEM, TEM) and biological (antimicrobial tests) approaches. The results demonstrated uniform silver nanoparticle formation on the substrate, and the developed nanomodified dressings were proven to have increased antimicrobial and antibiofilm potential. The developed wound dressings based on silver nanoparticles, sodium alginate and essential oils have real potential in treating infections, and can be investigated as an efficient alternative to antibiotics and topical preparations for wound management. MDPI 2020-04-03 /pmc/articles/PMC7178656/ /pubmed/32260273 http://dx.doi.org/10.3390/ma13071682 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Vasile, Bogdan Stefan Birca, Alexandra Catalina Musat, Mihaela Carmen Holban, Alina Maria Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections |
title | Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections |
title_full | Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections |
title_fullStr | Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections |
title_full_unstemmed | Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections |
title_short | Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections |
title_sort | wound dressings coated with silver nanoparticles and essential oils for the management of wound infections |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178656/ https://www.ncbi.nlm.nih.gov/pubmed/32260273 http://dx.doi.org/10.3390/ma13071682 |
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