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Preparation, carbonic anhydrase enzyme inhibition and antioxidant activity of novel 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives incorporating mono or dipeptide moiety

New dipeptide–dihydroquinolinone derivatives were successfully synthesised by benzotriazole mediated nucleophilic acyl substitution reaction and their structures were elucidated by spectroscopic and analytic techniques. The carbonic anhydrase (CA, EC 4.2.1.1) inhibitory activity of the new compounds...

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Detalles Bibliográficos
Autores principales: Küçükbay, Hasan, Gönül, Zeynep, Küçükbay, F. Zehra, Angeli, Andrea, Bartolucci, Gianluca, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178833/
https://www.ncbi.nlm.nih.gov/pubmed/32297533
http://dx.doi.org/10.1080/14756366.2020.1751620