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Serum-derived factors of breast cancer patients with brain metastases alter permeability of a human blood–brain barrier model
BACKGROUND: The most threatening metastases in breast cancer are brain metastases, which correlate with a very poor overall survival, but also a limited quality of life. A key event for the metastatic progression of breast cancer into the brain is the migration of cancer cells across the blood–brain...
Autores principales: | Curtaz, Carolin J., Schmitt, Constanze, Herbert, Saskia-Laureen, Feldheim, Jonas, Schlegel, Nicolas, Gosselet, Fabien, Hagemann, Carsten, Roewer, Norbert, Meybohm, Patrick, Wöckel, Achim, Burek, Malgorzata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178982/ https://www.ncbi.nlm.nih.gov/pubmed/32321535 http://dx.doi.org/10.1186/s12987-020-00192-6 |
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